Pinocembrin (PCB), a flavonoid known for its anti-inflammatory properties, has been approved for various clinical trial applications. To evaluate deeper into the anti-inflammatory potential of the specific enantiomer of natural PCB, we conducted the first investigation into the efficacy of the pure enantiomer (2)-PCB in modulating inflammatory mediators induced by lipopolysaccharide (LPS) in both murine RAW 264.7 and human U937 macrophage cell lines.
View Article and Find Full Text PDFConsidering the escalating resistance to conventional antifungal medications, it is critical to identify novel compounds that can efficiently counteract this challenge. The purpose of this research was to elucidate the fungicidal properties of secondary metabolites derived from , with a specific focus on their efficacy against species. This study utilized a combination approach comprising laboratory simulations and experiments to discern and evaluate the biologically active constituents present in the dichloromethane extract of .
View Article and Find Full Text PDFBACKGROUND Dragon fruit (Hylocereus polyrhizus) is one of the most common fruits in tropical countries, including Indonesia. The unique deep purple-colored pulp of the fruit is eaten whole and consumed as juice. However, the inedible thick peel is wasted, causing environmental issues.
View Article and Find Full Text PDFDisease causing bacteria such as and present a problem for fish farming. Treatment to remove them are generally carried out using antibiotics which have side effects on fish, the environment and humans. However, the use of antibacterial compounds derived from heterotrophic bacteria serve as a good alternative for antibiotics.
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