Effects of 3-methyl-5-isoxazole carboxylic acid on the plasma volume loss induced by thermal trauma.

The effects of 3-methyl-5-isoxazole carboxylic acid (MIC) on postburn plasma volume loss have been studied in the anesthetized dog, and the results demonstrated that, when administered before thermal trauma, MIC significantly reduces the plasma volume loss observed at 1 and 2 hours postburn. The reduction of plasma volume loss observed was less than that observed with nicotinic acid administered preburn. A single 0.

The presence of phytochrome in purified barley etioplasts and its in vitro regulation of biologically-active gibberellin levels in etioplasts.

Data are presented confirming that purified barley etioplasts contain, or have associated with them, consistently detectable amounts of photoreversible phytochrome. Etioplasts, separated from mitochondrial contamination by sucrose gradient centrifugation, respond in vitro to red light treatment by an increase in the level of extractable gibberellin-like substances. It is concluded that earlier reports of the substances.

Effects of reserpine upon thermal stress-induced cardiovascular changes.

The cardiovascular changes induced by 15% total body surface area third-degree burn have been studied in anesthetized dogs. The responses observed were a decrease in plasma volume, a decrease in cardiac output, and a slight but insignificant fall in mean arterial pressure. Graded doses of reserpine ranging from 0.

Effects of hyperbaric oxygen upon S. aureus, Ps. aeruginosa and C. albicans.

Numerous in vitro investigations have reported that prolonged, continuous hyperbaric oxygen (OHP) exposure to certain bacteria and yeast is bacteriostatic. While it is tempting to attribute the lower infection rates reported in OHP-treated patients to this bacteriostatic effect, the duration and intensity of OHP exposure in these experimental studies exceeds that of normal therapeutic use. This study was designed to investigate the effects of human OHP treatment protocols upon the in vitro growth and survival of Staphylococcus aureus, Pseudomonas aeruginosa, and Candida albicans.

Effects of beta adrenergic blocking agents upon thermal trauma induced cardiovascular changes.

The cardiovascular changes induced by 15% total body surface area 3 degrees burn have been studied in dogs anesthetized with sodium pentobarbital. The responses observed were a decrease in plasma volume, a decrease in cardiac output, and a slight but insignificant fall in mean arterial blood pressure. Beta adrenergic blockage with propranolol prior to thermal trauma reduced the plasma volume loss, increased the depression of cardiac output, and caused a rise in mean arterial blood pressure.

Influence of dietary ascorbic acid on plasma lipid levels in the rainbow trout.

Rainbow trout maintained on ascorbic acid deficient and three grades of ascorbic acid supplemented diets (160--1280 mg ascorbic acid pr kg feed) for a period of 53 weeks, were studied for effects on plasma lipid levels. Fish fed the diet with no ascorbic acid manifested lethargy, lordosis, scoliosis, internal hemorrhages and low body weight. With regard to blood properties, ascorbic acid deficient fish had low hematocrit and high plasma levels of triglycerides and cholesterol but low level of free fatty acids.

Effects of hydralazine on canine muscarinic ganglion stimulation.

The effects of hydralazine upon the caudal pressor responses during occlusion of the abdominal aorta and vena cava evoked by: (1) preganglionic electrical stimulation of the lumbar sympathetic chain, (2) neostigmine and (3) McN-A-343 were investigated in the anesthetized dog. Hydralazine (10 microgram/kg, i.v.

Tissue gases in human hypertrophic burn scars.

The partial pressures of oxygen and carbon dioxide have been measured in hypertrophic scars in burned patients, using mass spectroscopy. The pO2 in scar tissue was significantly depressed in comparison to the pO2 in normal dermis (a decrease of 13.1 +/- 2.

An in vitro association of soluble phytochrome with a partially purified organelle fraction from barley leaves.

Red light treatment in vitro increases the pelletability of phytochrome in homogenates of etiolated barley (Hordeum vulgare L. cv. 'Julia') leaves.

Effects of light on phytochrome in cauliflower curd.

The effect of light on the phytochrome content of cauliflower (Brassica oleracea (L.) var. botrytis) curd was studied using in vivo spectrophotometry.

DNA damage and repair in L1210 cells exposed to 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea.

The DNA of L1210 cells exposed to low concentrations of 1-(2-chloroethyl)=3-cyclohexyl-1-nitrosourea has been analyzed for the presence of single-strand breaks. DNA from 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea-treated cells both sediments more slowly than control DNA on alkaline sucrose gradients andshows a greater extent of strand separation of the DNA helix in alkali. These effects are a typical result of exposure of cellular DNA to alkylating agents or ionizing radiation.

The radiology of ex vivo renal perfusion and autotransplantation.

The radiologic findings in 16 patients subjected to ex vivo renal perfusion and autotransplantation are reviewed. Preoperative excretion urography and renal arteriography are essential to define ureteral and arterial anatomy; renal scintiangiography and renography are useful for baseline studies. Plain radiographs should be obtained during nephrolithotomy.

Chlorophyll interference with phytochrome measurement.

Measurements of phytochrome by Δ (ΔA725-815 nm) were completely suppressed at chlorophyll concentrations of the order of 20-40 μg g(-1) f.wt. in vivo and 37 μg cm(-3) in vitro, and the readings were reduced by 50% at only 12 μg cm(-3) in vitro.