[Description and validity of Enedam test-retest. A structured interview for the diagnosis of Alzheimer's, multi-infarction dementias and dementias of other etiologies based on the CIE-10 and DSM-III-R].

The SIDAM, a new clinical structured interview for the diagnosis and measure of dementia according to DSM-III-R and ICD-10, is described. This instrument comprises a clinical overview, several cognitive tests, including the Mini-Mental State, and a section for clinical judgement and information coming from others. Every item relies on DSM-11-R and ICD-10 algorithms.

Development of diagnostic checklists for use in routine clinical care. A guideline designed to assess DSM-III-R diagnoses.

To enhance diagnostic assessment in routine clinical care, the Munich Diagnostic Checklists have been developed for a systematic criteria-related evaluation of the most common psychiatric disorders according to DSM-III-R. Design, concept, and areas of application of the instrument are described. An initial test-retest study showed that satisfactory to excellent diagnostic agreement can be reached.

Identical pattern of acute rejection after isolated islet and vascularized whole-pancreas transplantation in the rat.

The course of acute rejection of major histocompatibility complex (MHC)-incompatible isolated rat pancreatic islets transplanted under the kidney capsule was monitored functionally and histologically from day 1 to 10. The patterns observed were compared to those of vascularized whole-pancreas transplants with preserved and suppressed exocrine secretion. In addition the morphologic reactions after isogenic transplantation of islets or whole-pancreas transplants are described.

Immunohistochemical evidence for IgE involvement in Graves' orbitopathy.

Orbital muscle and adipose tissues from seven Graves' orbitopathy patients were studied with in situ assays for IgE. The cases varied in disease severity and site biopsied. Two monoclonal and one polyclonal anti-IgE reagents produced similar results.

[Primary and secondary process thinking in normal probands, neurotic and borderline patients].

In the present paper normals, neurotics and borderline patients were compared with respect to primary and secondary process thinking. The Holtzman Inkblot Technique was used to assess the different modes of functioning. As it was expected, normals had more indicators of the most severe levels of primary process thinking than neurotics, but less than borderline patients.

Different effects of prolonged exercise on the right and left ventricles.

To examine the functional consequences of the greater increase in right ventricular work with exercise, the effects of prolonged exercise on the right and left heart chambers were compared in 41 athletes before, at the finish (13 min) and after recovery (28 h) from the Hawaii Ironman Triathlon (3.9 km swim, 180.2 km bike ride, 42.

Iron Status in Ultraendurance Triathletes.

In brief: Using several hematologic indexes, researchers examined the iron status of 50 ultraendurance athletes participating in the 1988 Ironman Triathlon in Hawaii. Fifteen (30%) of the 50 triathletes had at least one suboptimal iron index: Two exhibited stage 2 iron deficiency in the presence of normal hemoglobin levels; eight had normal ferritin levels but subnormal levels of transferrin saturation and iron; three had abnormal levels of total iron-binding capacity; and two had low hemoglobin levels with all other iron indices normal, which indicated dilutional anemia. These data suggest that several indexes need to be examined when assessing the iron status of triathletes and that unusual values do not necessarily reflect actual iron deficiency.

Lactate, oxygen uptake, and cycling performance in triathletes.

To assess the relationship of exercise test variables to each other and to bike race times in an ultra-distance triathlon, we studied 24 participants (14 men, 10 women) in the 1985 Hawaii Ironman Triathlon, using a graded, maximal cycle ergometer test with gas exchange and blood lactate (LA) measurements at each work load. Exercise test variables were oxygen uptake (VO2) and heart rate (HR) at the lactate and ventilatory thresholds. Lactate threshold (LT-1) was defined as the exercise intensity that elicited a 1 mM increase in blood lactate concentration above the value measured during the first work load for each subject.

Applied physiology of a triathlon.

The triathlon is an endurance contest in which contestants must compete in 3 consecutive events, usually swimming, cycling and running. Success in a triathlon depends upon the ability of the triathlete to perform each of the sequential events at optimal pace without creating fatigue that will hinder performance in the next event. The successful triathlete must, therefore, have highly developed oxygen transport and utilisation systems as well as the ability to efficiently produce a high energy output for prolonged periods without creating metabolic acidosis.

Dehydration and hyponatremia during triathlons.

In ultraendurance triathlons, dehydration and electrolyte balance are important factors in race completion and level of performance. Dehydration is the most common reason for a triathlete in the Hawaii Ironman Triathlon to need medical assistance. Hyponatremia is the predominant electrolyte disturbance.

Protein and energy metabolism during prolonged exercise in trained athletes.

Unlabelled: Eight elite triathlon athletes participated in a laboratory study of the effects of endurance exercise on protein and energy metabolism. The study consisted of 3 h of cycling and 5 h of treadmill running; 3.5 h before beginning the exercise, a primed constant infusion of 1-13C leucine and 6,6(-2)H glucose was begun.

A systematic evaluation of the DSM-III-R criteria for alcohol dependence.

The diagnostic efficiency of the nine DSM-III-R criteria (signs and symptoms) for alcohol dependence was systematically investigated in a sample of 215 psychiatric outpatients. Specificity was generally greater than 0.90, but two groups of criteria were distinguished according to high v moderate sensitivity rates.

Structure of leuconolam sesquihydrate.

8a-Ethyl-7,8,8a,10,11,12a-hexahydro-12a- hydroxyindolizino[8,1-ef][1]benzazonine-6,13-(5H,9H)-dione sesquihydrate, C19H22N2O3.3/2H2O, Mr = 353.42, triclinic, P1, a = 9.

Prevalence of multivalvular regurgitation in athletes.

To assess the effects of exercise training on the prevalence of valvular regurgitation, 2-dimensional echocardiography and Doppler flow mapping were performed in 45 athletes and 26 sedentary control subjects of similar age and sex. Mitral, tricuspid, aortic and pulmonic regurgitations were sought in all possible views and mitral and tricuspid flow velocities were recorded. Mitral and tricuspid anulus diameters and the maximal areas of regurgitant flow were planimetered.

Overuse injuries in ultraendurance triathletes.

Overuse injuries represent the largest percentage of sports-related injuries requiring medical treatment. These injuries represent a substantial health issue for the millions of adults who have made physical activity an integral part of their lifestyle, but may be even more important to those pursuing ultraendurance exercise. The purposes of this study were to report the type and incidence of overuse injuries in ultraendurance triathletes and to relate training practices to injury occurrence.

Anxiety disorders: a comparison of the ICD-9 and DSM-III-R classification systems.

Corresponding categories for anxiety disorders, as defined by the classification systems of the ICD-9 and the DSM-III-R, were compared in a selected sample of 114 outpatients. An unequivocal category-to-category correspondence could not be demonstrated for any diagnosis. Anxiety states in ICD-9 were closely related to generalized anxiety and panic disorder in DSM-III-R, and most patients diagnosed as phobic according to ICD-9 received one of the specific phobia diagnoses of DSM-III-R.

Endurance exercise in the presence of heart disease.

Although patients with heart disease have successfully completed marathon runs, the immediate cardiac effects of similar and greater distance endurance exercise competition are unknown. Two such cases are presented, demonstrating that vigorous exercise and extreme levels of fitness are not precluded in the cardiac patient.

The overlap between depression and anxiety on different levels of psychopathology.

Symptoms, syndromes, and diagnoses (DSM-III-R) for depression and anxiety were assessed and evaluated in 150 psychiatric outpatients. It was hypothesized that the coexistence of depression and anxiety within subjects strongly depends on the psychopathological level determined. The results confirmed this assumption.

Alcohol dependence in ICD-9 and DSM-III-R: a comparative polydiagnostic study.

Diagnoses of alcohol dependence, using the classification systems ICD-9 and DSM-III-R, were compared in a sample of 215 psychiatric outpatients. A lower diagnostic threshold was obtained for DSM-III-R. This category tended to be more inclusive for relatively mild forms of inadequate alcohol use.