A Toxic Environment: a Growing Understanding of How Microbial Communities Affect Escherichia coli O157:H7 Shiga Toxin Expression.

Enterohemorrhagic (EHEC) strains, including O157:H7, cause severe illness in humans due to the production of Shiga toxin (Stx) and other virulence factors. Because Stx is coregulated with lambdoid prophage induction, its expression is especially susceptible to environmental cues. Infections with Stx-producing can be difficult to model due to the wide range of disease outcomes: some infections are relatively mild, while others have serious complications.

A Putative Microcin Amplifies Shiga Toxin 2a Production of Escherichia coli O157:H7.

O157:H7 is a foodborne pathogen implicated in various multistate outbreaks. It encodes Shiga toxin on a prophage, and Shiga toxin production is linked to phage induction. An strain, designated 0.