Publications by authors named "Hillary L Graham"
Placental Abruption and Cardiovascular Event Risk (PACER): Design, data linkage, and preliminary findings.
Paediatr Perinat Epidemiol
March 2024
Article Synopsis
- Obstetrical complications, particularly placental abruption, can significantly impact the long-term health of mothers and children, potentially leading to increased rates of chronic diseases, especially cardiovascular issues.
- The PACER cohort study links extensive vital records data from over 1.8 million birthing individuals in New Jersey between 1993 and 2020, utilizing a robust probabilistic algorithm to track health outcomes throughout their lives.
- Preliminary findings show a notable prevalence of abruption (1.1%) and high linkage rates for health events, indicating that studying these connections may provide valuable insights into the links between pregnancy complications and cardiovascular disease risk.
Objective: Preeclampsia is an important risk factor for cardiovascular disease (CVD, including heart disease and stroke) along the life course. However, whether exposure to chronic hypertension in pregnancy, in the absence of preeclampsia, is implicated in CVD risk during the immediate postpartum period remains poorly understood. Our objective was to estimate the risk of readmission for CVD complications within the calendar year after delivery for people with chronic hypertension.
View Article and Find Full Text PDFBackground: There are limited data on postpartum readmissions for depression in the United States (US). Specifically, the extent to which ischaemic placental disease (IPD) during pregnancy predisposes patients to develop postpartum depression remains poorly understood. We investigated whether IPD is associated with postpartum readmission for new-onset depression in the first year after delivery.
View Article and Find Full Text PDFBackground: Given slowing secular declines and persistent racial disparities, stillbirth remains a major health burden in the US. We investigate changes in stillbirth rates overall and for Black and White women, and determine how maternal age, delivery year (period), and birth year (cohort) have shaped trends.
Methods: We designed a sequential time-series analysis utilising the 1980 to 2020 US vital records data of live births and stillbirths at ≥24 weeks gestation.
Background: Whether changes in stroke mortality are affected by age distribution and birth cohorts, and if the decline in stroke mortality exhibits heterogeneity by stroke type, remains uncertain.
Methods: We undertook a sequential time series analysis to examine stroke mortality trends in the USA among people aged 18-84 years between 1975 and 2019 (n = 4 332 220). Trends were examined for overall stroke and by ischaemic and haemorrhagic subtypes.
Objective:: Reports from the National Center for Health Statistics suggest that maternal mortality rates in the United States increased after the introduction of the pregnancy status checkbox on the 2003 revised US standard death certificate; however, this increase was because of an artifact of surveillance. This study aimed to evaluate the trends in cardiovascular disease (CVD)-related pregnancy-associated mortality in the United States and assess the impact of ascertainment by death certificate type using national- and state-level data.
Study Design:: We conducted a cross-sectional analysis of all live births and CVD-related pregnancy-associated deaths in the United States (1999–2018) based on the National Vital Statistics System data.