A diet rich in docosahexaenoic acid enhances reactive astrogliosis and ramified microglia morphology in apolipoprotein E epsilon 4-targeted replacement mice.

Docosahexaenoic acid (DHA) consumption reduces spatial memory impairment in mice carrying the human apolipoprotein E ε4 () allele. The current study evaluated whether astrocyte and microglia morphology contribute to the mechanism of this result. and mice were fed either a DHA-enriched diet or a control diet from 4 to 12 months of age.

Omega-3 PUFA metabolism and brain modifications during aging.

In Canada, 5.5 million (16% of Canadians) adults are >65 years old and projections suggest this number will be approximately 20% of Canadians by 2024. A major concern regarding old age is a decline in health, especially if this entails a loss of self-sufficiency and independence caused by a decline in cognition.