Reduced benefit from long-term item frequency contributes to short-term memory deficits in dyslexia.

Dyslexia, a specific difficulty in acquiring proficient reading, is also characterized by reduced short-term memory (STM) capacity. Extensive research indicates that individuals with developmental dyslexia (IDDs) benefit less from exposure, and this hampers their long-term knowledge accumulation. It is well established that long-term knowledge has a great effect on performance in STM tasks, and thus IDDs' reduced benefit of exposure could potentially reduce their relative performance in such tasks, especially when frequent items, such as digit-words, are used.

Training-induced improvement in working memory tasks results from switching to efficient strategies.

It is debated whether training with a working memory (WM) task, particularly n-back, can improve general WM and reasoning skills. Most training studies found substantial improvement in the trained task, with little to no transfer to untrained tasks. We hypothesized that training does not increase WM capacity, but instead provides opportunities to develop an efficient task-specific strategy.

Short-term memory capacity and sensitivity to language statistics in dyslexia and among musicians.

Poor short-term memory (STM) capacity in individuals with dyslexia (IDDs) and enhanced STM capacity in musicians are well documented, yet their causes are disputed. Previous studies also found poor use of stimuli statistics by IDDs and enhanced use by musicians. We hypothesized that these observations are functionally related, as follows: Enhanced sensitivity to statistics facilitates musicians' benefit from each exposure, and reduced sensitivity to statistics hinders IDDs' benefit.

Auditory frequency discrimination is correlated with linguistic skills, but its training does not improve them or other pitch discrimination tasks.

Brain-training, aimed at advancing and improving cognitive and perceptual abilities, is vastly studied because of its immense promise. Yet, there are major controversies regarding its main claim that intensive weeks' training on a single challenging task could improve performance in related untrained tasks. Ample training studies showing transfer were criticized for flawed design.

Electrophysiological correlates of speech perception mechanisms and individual differences in second language attainment.

In an increasingly globalized world mastering a second language (L2) provides a clear advantage. However, after early childhood, not everyone can easily learn a foreign language. The present study explored whether the large variability found in L2 attainment in the normal population, not diagnosed as learning disabled, is related to preattentive speech perception abilities.

Crystal structure of a type-II cohesin module from the Bacteroides cellulosolvens cellulosome reveals novel and distinctive secondary structural elements.

The incorporation of enzymes into the multi-enzyme cellulosome complex and its anchoring to the bacterial cell surface are dictated by a set of binding interactions between two complementary protein modules: the cohesin and the dockerin. In this work, the X-ray crystal structure of a type-II cohesin from scaffoldin A of Bacteroides cellulosolvens has been determined to a resolution of 1.6 angstroms using molecular replacement.