Publications by authors named "Hilda Holtsema"

Article Synopsis
  • Congenital anomalies are a significant global health concern, but data on their prevalence in the Caribbean, specifically the ABC islands (Aruba, Bonaire, and Curaçao), is limited.
  • A study was conducted to assess the prevalence of these anomalies using data from live births and stillbirths between 2008 and 2017, finding a total prevalence rate of 242.97 per 10,000 births, with Bonaire reporting the highest rates.
  • The study revealed that while the overall prevalence in the ABC islands is comparable to that of the French West Indies, it is lower than in the Northern Netherlands; specific anomalies like polydactyly were notably more prevalent in the ABC islands compared to other regions.
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Objective: Serum cancer antigen (CA) 125 is the only biomarker used frequently in women with or at risk for ovarian cancer. However, the same reference level is used before and after (prophylactic) bilateral salpingo-oophorectomy (BSO). We evaluated the effect of BSO on CA125 level in BRCA mutation carriers and tested which factors interact with the change in CA125 level.

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Postpartum haemorrhage may be a life threatening complication. Seven cases are described in which the B-Lynch surgical technique (a brace like suture over the uterus) was successful in obtaining haemostasis. In four cases, the B-Lynch technique was the first line of treatment.

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