Publications by authors named "Hilal Irmak Sapmaz"

Article Synopsis
  • The study investigates the impact of COVID-19 on olfactory pathways by analyzing 63 autopsy cases, comparing 37 COVID-19 victims with 26 non-COVID controls.
  • Researchers measured various anatomical structures in the olfactory system and found significant reductions in the volume, weight, and dimensions of the olfactory bulbs and tracts in the COVID-19 group.
  • The findings suggest that COVID-19 causes notable damage to the olfactory centers, indicating the importance of understanding these changes for clinical and future research efforts related to the disease.
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Purpose: This study aims to determine the presence and morphology of triticeal cartilage (TrC) through autopsy cases and to examine its relationship with age, gender, and height, thus contributing to clinical practices and forensic perspective.

Materials And Methods:  Our study was conducted on a total of 84 autopsy cases between the ages of 20-90 years who came to Tokat Forensic Medicine Institute. The laryngeal region was palpated to determine whether TrC was present.

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Objective: To investigate the effect of hard palate angulation caused by septal deviation on the volume of the maxillary sinus.

Methods: Coronal computed tomographic (CT) scans of 1568 patients aged from 18 to 60 were examined. CT scans of 402 patients were included in the study.

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Objective: Aquaporin (AQP) 1 and AQP 4 are expressed in human heart and several studies have been focused on these two aquaporins. For this purpose, the present study is aimed to research the effects of aging on AQP 1 and AQP 4 in heart tissue.

Methods: In this study, 14 Balb/C type white mice were used.

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Intraperitoneal (i.p.) injection is the most frequently used method for implementing parenteral therapies in rats and mice.

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Aim: The aim of this study was to investigate the effects of carvedilol (CVD) on experimentally induced ovarian ischemia/reperfusion (I/R) injury in rats.

Methods: An ovarian I/R model was applied to rats, classified into three groups: 1 (n = 7), sham operated (control); 2 (n = 7), 3 h ischemia + 3 h reperfusion (I/R); 3 (n = 7), 3 h ischemia + CVD + 3 h reperfusion (I/R + CVD). Malondialdehyde (MDA) levels and glutathione peroxidase (GSH-Px) and superoxide dismutase (SOD) activities in ovarian tissues and serum were measured.

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Conclusion: The increased AQP5 expression associated with ageing in glands, which mainly secreted a serous solution, suggests a compensation for the decreased amount of saliva secretion associated with age progression.

Objective: To investigate the change in aquaporin-1 (AQP1) and aquaporin-5 (AQP5) expression in the salivary glands in young and elder mice.

Materials And Method: Twelve female mice from the Balb/C genus (30-50 g) were used.

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Objective: To assess the usability of lavender oil as an adjuvant in the medical treatment of pain due to renal stones.

Methods: One hundred patients age 19-64 years diagnosed with renal colic were included in the study. Group 1 (n=50) received standard medical therapy (diclofenac sodium, 75 mg intramuscularly); group 2 (n=50) received aromatherapy (lavender oil) in addition to the standard medical treatment.

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Aim: This study was carried out to determine the effects of formaldehyde (FA) inhalation on the humoral immunity of rats and the protective effect of Nigella sativa (NS) oil.

Materials And Methods: The rats (n = 33) were divided into five groups, with five animals in the control group (FA-free air) and seven in the other four groups. Group FA1 was exposed to FA (5 ppm), group FA + NS1 was treated with NS and exposed to FA (5 ppm), group FA2 was exposed to FA (10 ppm), and group FA + NS2 was treated with NS and exposed to FA (10 ppm).

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The effects of montelukast against methotrexate-induced liver damage were investigated. 35 Wistar albino female rats were divided into 5 groups as follows: group I: control; group II: montelukast (ML); group III: methotrexate (Mtx); group IV: montelukast treatment after methotrexate application (Mtx + ML); group V: montelukast treatment before methotrexate application (ML + Mtx). At the end of the experiment, the liver tissues of rats were removed.

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Toluene is a clear, colorless and volatile hydrocarbon that is metabolized in liver, produced free oxygen radicals and can mediate cellular damage. Melatonin which is a pineal gland hormone is a very potent antioxidant. It can make the cellular membrane more durable against oxidative attacks and protect nuclear DNA from oxidative damage.

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Article Synopsis
  • This study looked at how montelukast, a medication, can help protect against kidney damage caused by a drug called cisplatin (CP).
  • They tested this on 35 female rats, dividing them into five groups to see different effects of the treatments.
  • The results showed that montelukast helped improve the kidney health of rats harmed by cisplatin, making it a potential treatment for this type of kidney damage.
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