Paediatric handgrip reference curves and the relationship between lower handgrip strength and clinical outcomes of hospitalised children.

Aim: There is a need for population-based reference values of handgrip strength, which is an objective measurement reflecting muscle status, in the paediatric population and there is limited data on the prognostic importance of handgrip strength. The aim of the study was to establish reference percentiles for handgrip strength in healthy Turkish children and to investigate the relationship between handgrip strength and clinical outcomes in hospitalised children.

Methods: A total of 1437 healthy children and 103 hospitalised children aged 6-16 years were included in this cross-sectional study.

Effect of low level laser therapy and zoledronate on the viability and ALP activity of Saos-2 cells.

A limited number of clinical studies indicate the supportive role of low level laser therapy (LLLT) on medical and/or surgical approaches carried out in treatment modalities for bisphosphonate related necrosis of jaws (BRONJ), the most common side effect of bisphosphonates used to inhibit bone resorption. The purpose of this study was to investigate the effects of LLLT on cell proliferation and alkaline phosphatase (ALP) activity of human osteoblast-like cells (Saos-2) treated with different doses of zoledronate, the most potent bisphosphonate. Saos-2 cells were treated with different concentrations of zoledronate and were irradiated with diode laser (wavelength 808 nm, 10 s, 0.