Publications by authors named "Hikaru Niitsu"
Objective: To investigate differences in uptake regions between methyl-C-L-methionine positron emission tomography (C-MET PET) and gadolinium (Gd)-enhanced magnetic resonance imaging (MRI), and their impact on dose distribution, including changing of the threshold for tumor boundaries.
Methods: Twenty consecutive patients with grade 3 or 4 glioma who had recurrence after postoperative radiotherapy (RT) between April 2016 and October 2017 were examined. The study was performed using simulation with the assumption that all patients received RT.
Background: Follow-up after treatment for hepatocellular carcinoma (HCC) can be mostly performed using dynamic CT or MRI, but there is no common evaluation method after radiation therapy. The purpose of this study is to examine factors involved in tumor reduction and local recurrence in patients with HCC treated with proton beam therapy (PBT) and to evaluate HCC shrinkage after PBT.
Methods: Cases with only one irradiated lesion or those with two lesions irradiated simultaneously were included in this study.
Article Synopsis
- The study aimed to evaluate the effectiveness and safety of proton beam therapy (PBT) for treating hepatocellular carcinoma (HCC) with bile duct invasion (BDI), which generally has a poor prognosis and lacks standardized treatment protocols.
- 15 patients received PBT between 2009 and 2018, with findings showing 1-, 2-, and 3-year overall survival rates of 80.0%, 58.7%, and 40.2%, indicating some level of positive outcome, though with significant toxicity risks.
- Results indicated that while PBT is feasible for managing BDIHCC with manageable side effects, it still requires careful consideration due to the occurrence of