Publications by authors named "Hikaru Negishi"
Int J Lab Hematol
November 2024
Article Synopsis
- Researchers explored the connection between DNA repair gene polymorphisms, specifically in base excision repair (BER) genes, and the risk of developing acute myeloid leukemia (AML).
- A significant association was found between the APEX1-656 T>G polymorphism and AML risk, with elevated expression of APEX1 observed in AML patients compared to healthy controls.
- The study concluded that APEX1 polymorphisms may be a risk factor for AML and emphasized APEX1's role in controlling AML cell differentiation and growth.
