Publications by authors named "Hikaru Koishihara"
Article Synopsis
- Research is advancing in understanding strigolactone (SL) biosynthesis and signaling, with the D14 receptor's crystal structure being resolved, but no inhibitors for SL signaling have been identified yet.*
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- The study utilized virtual screening with LigandScout to discover chemical regulators that could hinder SL reception, leading to the identification of a candidate compound, XM-47.*
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- XM-47 was found to inhibit interactions between D14 and its proteins SLR1 and D53, and its hydrolysis product, 2-MN, not only inhibits these interactions but also promotes the growth of rice tillering buds affected by strigolactone.*
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