Manganese oxide nanoparticle-assisted laser desorption/ionization mass spectrometry for medical applications.

We prepared and characterized manganese oxide magnetic nanoparticles ( =5.6 nm) and developed nanoparticle-assited laser desorption/ionization (nano-PALDI) mass spectrometry. The nanoparticles had MnO and MnO cores conjugated with hydroxyl and amino groups, and showed paramagnetism at room temperature.