Publications by authors named "Hikari Shimoda"
Objective: While several studies reported epidermal growth factor receptor (EGFR) expression in salivary gland cancer (SGC), results varied due to a lack of unified definition of EGFR positivity. In this study, we assessed the EGFR expression level using both EGFR positive score and cumulative EGFR score in the patients with SGC.
Methods: Between January 2010 and April 2021, 102 patients with SGC who underwent surgical resection were reviewed retrospectively by immunohistochemistry.
Article Synopsis
- Adenoid cystic carcinoma (AdCC) of the salivary gland is a slow-growing cancer that can sometimes spread to distant sites, although not commonly through lymph nodes.
- A study of 175 patients without lymph node metastasis identified key prognostic factors that influence disease free survival (DFS), distant metastasis free survival (DMFS), and overall survival (OS), particularly focusing on positive surgical margins and tumor stage.
- The findings showed that patients with no positive prognostic factors (PS0) had significantly better 10-year survival rates compared to those with one or more positive factors (PS1, PS2), indicating the importance of these factors in predicting patient outcomes.
Incidence and spread pattern of lymph node metastasis from submandibular gland cancer.
Eur Arch Otorhinolaryngol
September 2023
Objectives: To clarify the indication of neck dissection (ND) for patient with submandibular gland (SMG) cancer.
Methods: A total of 43 patients with SMG cancer were retrospectively analyzed. Forty-one patients underwent ND: Levels I-V in 19 patients, Levels I-III in 18 patients, and Level Ib in 4 patients.
Objective: We investigated the factors affecting postoperative parathyroid gland (PTG) function and devised an objective index to predict the postoperative PTG function during total thyroidectomy.
Method: This was a retrospective clinical review of 21 consecutive patients who were diagnosed with papillary thyroid carcinoma and underwent total thyroidectomy. The maximum intensity ratio (MIR) was determined as the maximum fluorescence intensity after ICG injection divided by the intensity before ICG injection.
To clarify the patterns of the recurrence and to assess the oncological and functional outcomes after salvage surgery for the patients with structural local recurrence of papillary thyroid cancer (PTC), twenty-five patients who underwent salvage surgery for structural local recurrence of PTC were retrospectively reviewed. Structural recurrences were observed in the tracheal lumen in 5 patients, intraluminal or intramuscular esophagus in 5 patients, trachea, and cricoid cartilage in 9 patients, cricoid and thyroid cartilage in 2 patients, intra-lumen of the larynx in 1 patient and soft tissue around thyroid in 3 patients, respectively. Although all local disease was resected with macroscopically negative margin, 10 patients diagnosed as microscopically positive margin.
View Article and Find Full Text PDFBackground: Extirpation of tumors arising in the pterygopalatine fossa is challenging because of its anatomic complexity.
Methods And Results: A 67-year-old man was referred to our department with a diagnosis of a tumor in his left pterygoid fossa. An incisional biopsy through the canine fossa was diagnosed as myxofibrosarcoma.