Publications by authors named "Hikari Seki"

Article Synopsis
  • - The study explored how body fat distribution affects left atrial (LA) size and its potential to reverse in nonobese atrial fibrillation (AF) patients, revealing a link between central fat and LA remodeling.
  • - A total of 116 nonobese AF patients underwent catheter ablation, and measures like body mass index (BMI) and waist-to-hip (W/H) ratio were analyzed alongside fat percentages to see their impact on LA volume changes over six months.
  • - Results showed that higher W/H ratios and central fat percentages were associated with ongoing LA enlargement post-ablation, emphasizing the need to evaluate body fat distribution, even in patients who are not obese.
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Article Synopsis
  • This study examined 183 AF patients undergoing CA, finding that 18% had LA hypertension, which was associated with larger LA volume, reduced reservoir strain, and increased stiffness.
  • Factors like waist circumference, C-reactive protein levels, and LA stiffness were independently linked to LA hypertension, indicating that LA stiffness derived from echocardiography could help detect LA hypertension prior to CA.
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Aims: Patients with chronic coronary syndrome (CCS) suffer from subsequent cardiovascular events, even after complete revascularization; thus, elucidation of the underlying pathophysiological mechanisms is required. Epicardial adipose tissue (EAT) is increasingly recognized as a metabolically active organ with a key role in the pathogenesis of metabolic-related cardiac diseases. The present study investigated the association between EAT burden and left heart remodelling in patients with CCS.

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Onco-cardiology is the emerging field, and the concept of shared risk factor holds an important position in this field. The increasing prevalence of colorectal cancer (CRC) in young adults is a critical epidemiological issue. Although metabolic syndrome, which is a major risk factor for cardiovascular disease, is known to be associated with CRC incidence in middle-aged and elderly individuals, it is unclear whether this association is present in young adults.

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Context: Although diabetes mellitus (DM) was reported to be associated with incident colorectal cancer (CRC), the detailed association between fasting plasma glucose (FPG) and incident CRC has not been fully understood.

Objective: We assessed whether hyperglycemia is associated with a higher risk for CRC.

Design: Analyses were conducted using the JMDC Claims Database [n = 1 441 311; median age (interquartile range), 46 (40-54) years; 56.

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Serum uric acid (SUA) was reported to be associated with incident cardiovascular disease (CVD). However, the relationship between SUA and CVD among young adults has not been clarified yet. In this study, we aimed to identify the association of medication naïve SUA with incident CVD including myocardial infarction (MI), stroke, heart failure (HF) and atrial fibrillation (AF) using a nationwide epidemiological database.

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Background: We aimed to explore the association between the blood pressure (BP) classification defined by the 2017 American College of Cardiology (ACC)/American Heart Association (AHA) guideline and the prevalence of retinal atherosclerosis.

Methods: This study was a retrospective observational cross-sectional analysis using the JMDC Claims Database. We analyzed 280,599 subjects not taking any antihypertensive medications.

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