[A Case of Renal Cell Carcinoma with Solitary Mammary Metastasis 28 Years after Surgery].

Metastatic breast tumors account for 0.5-2.0% of all malignant breast tumors; however, metastasis of renal cell carcinoma to the breast is extremely rare.

[A Case of Isolated Nipple Recurrence 22 Years after Breast Conserving Surgery for Breast Cancer].

An 80-year-old woman with left breast cancer was treated with breast-conserving surgery. After 22 years, she visited our hospital with a chief complaint of bloody secretion from left nipple. A biopsy showed ductal carcinoma, and she was diagnosed with nipple recurrence of breast cancer.

[A Case of Advanced Breast Cancer with SP142/22C3 Double Positive and BRCA Mutation Positive].

A 35-year-old woman was diagnosed as triple-negative breast cancer(TNBC)by a core needle biopsy and referred to our hospital. She was diagnosed as cT2N3M1, cStage Ⅳ TNBC because of metastasis in the right axilla, supraclavicular and internal mammary lymph node, and the contralateral supraclavicular lymph node in addition to the primary tumor. No obvious visceral metastasis was observed.

[Breast Cancer Therapy Strategies Based on the BRCA Pathogenic Variants].

Background: Breast cancer therapy based on the pathogenic variants of BRCA is entering a new era with the expanded use of olaparib in adjuvant chemotherapy. This study examined the timing of olaparib administration in patients with BRCA pathogenic sequence variant (PSV).

Subject And Methods: BRCA genetic testing was performed in 281 patients at our facility between April 2019 and October 2023.