Fucoxanthin extracted from Laminaria Japonica inhibits metastasis and enhances the sensitivity of lung cancer to Gefitinib.

Ethnopharmacological Relevance: Laminaria japonica, a brown seaweed, has been used in Traditional Chinese Medicine (TCM) to treat a variety of diseases including lung cancer.

Aim Of The Study: To demonstrate the effects of Fucoxanthin (FX), a major active component extracted from Laminaria japonica on metastasis and Gefitinib (Gef) sensitivity in human lung cancer cells both in vitro and in vivo.

Materials And Methods: Invasion and migration of lung cancer cells were detected using the wound healing assay and transwell assay.

H+-ATPase activity in Bifidobacterium with special reference to acid tolerance.

The acid tolerance of 17 strains of nine species of bifidobacteria was compared using brief exposures to acidic conditions (pH 2-5). In addition, because it has been hypothesized that the acid tolerance of bifidobacteria depends on H+-ATPase activity, the activity of this enzyme in various strains and species was compared. In general, the acid tolerance of bifidobacteria was found to be weak, with the exception of Bifidobacterium lactis and Bifidobacterium animalis.

Inhibition of Helicobacter pylori infection by orally administered yolk-derived anti-Helicobacter pylori antibody.

Background/aims: We studied highly specific chicken egg yolk-derived anti-Helicobacter pylori antibody, and examined efficacy in inducing passive immunity and a bacteriostatic effect on H. pylori.

Methodology: Heat-killed H.

Adhesive property of Bifidobacterium lactis LKM512 and predominant bacteria of intestinal microflora to human intestinal mucin.

The adhesive property to the intestinal mucin of Bifidobacterium lactis LKM512, B. longum, B. breve, B.