In medical applications-such as positron emission tomography (PET)-511 keV photons that experience Compton scattering are studied. We present a consistent framework based on quantum error-correction channels-intensively studied in quantum computing-to fully describe the quantum information-theoretic content of high energetic photons undergoing Compton scattering, characterized by the Klein-Nishina formula in unoriented matter. In this way, we can predict the expected spatial distribution of two or more, pure or mixed, polarization entangled or separable photons.
View Article and Find Full Text PDFDiscrete symmetries play an important role in particle physics with violation of CP connected to the matter-antimatter imbalance in the Universe. We report the most precise test of P, T and CP invariance in decays of ortho-positronium, performed with methodology involving polarization of photons from these decays. Positronium, the simplest bound state of an electron and positron, is of recent interest with discrepancies reported between measured hyperfine energy structure and theory at the level of 10 signaling a need for better understanding of the positronium system at this level.
View Article and Find Full Text PDFBackground: Alongside the benefits of Total-Body imaging modalities, such as higher sensitivity, single-bed position, low dose imaging, etc., their final construction cost prevents worldwide utilization. The main aim of this study is to present a simulation-based comparison of the sensitivities of existing and currently developed tomographs to introduce a cost-efficient solution for constructing a Total-Body PET scanner based on plastic scintillators.
View Article and Find Full Text PDFIn positron emission tomography (PET) studies, convolutional neural networks (CNNs) may be applied directly to the reconstructed distribution of radioactive tracers injected into the patient's body, as a pattern recognition tool. Nonetheless, unprocessed PET coincidence data exist in tabular format. This paper develops the transformation of tabular data into n-dimensional matrices, as a preparation stage for classification based on CNNs.
View Article and Find Full Text PDFBound entanglement, in contrast to free entanglement, cannot be distilled into maximally entangled states by two local observers applying measurements and utilizing classical communication. In this paper we ask whether a relativistic observer classifies states according to being separable, bound or free entangled in the same manner as an unboosted observer. Surprisingly, this turns out not to be the case.
View Article and Find Full Text PDFEntanglement witnesses (EWs) are a versatile tool in the verification of entangled states. The framework of mirrored EW doubles the power of a given EW by introducing its twin-a mirrored EW-whereby two EWs related by mirroring can bound the set of separable states more efficiently. In this work, we investigate the relation between the EWs and its mirrored ones, and present a conjecture which claims that the mirrored operator obtained from an optimal EW is either a positive operator or a decomposable EW, which implies that positive-partial-transpose entangled states, also known as the bound entangled states, cannot be detected.
View Article and Find Full Text PDFBackground: The Jagiellonian Positron Emission Tomograph is the 3-layer prototype of the first scanner based on plastic scintillators, consisting of 192 half-metre-long strips with readouts at both ends. Compared to crystal-based detectors, plastic scintillators are several times cheaper and could be considered as a more economical alternative to crystal scintillators in future PETs. JPET is also a first multi-photon PET prototype.
View Article and Find Full Text PDFWe compare the classification as entangled or separable of Bell diagonal bipartite qudits with positive partial transposition (PPT) and their properties for different dimensions. For dimension [Formula: see text], a form of entanglement exists that is hard to detect and called bound entanglement due to the fact that such entangled states cannot be used for entanglement distillation. Up to this date, no efficient solution is known to differentiate bound entangled from separable states.
View Article and Find Full Text PDFWith a probability of success of 95% we solve the separability problem for Bell diagonal qutrit states with positive partial transposition (PPT). The separability problem, i.e.
View Article and Find Full Text PDFIn vivo assessment of cancer and precise location of altered tissues at initial stages of molecular disorders are important diagnostic challenges. Positronium is copiously formed in the free molecular spaces in the patient’s body during positron emission tomography (PET). The positronium properties vary according to the size of inter- and intramolecular voids and the concentration of molecules in them such as, e.
View Article and Find Full Text PDFEntanglement detection in high dimensional systems is a NP-hard problem since it is lacking an efficient way. Given a bipartite quantum state of interest free entanglement can be detected efficiently by the PPT-criterion (Peres-Horodecki criterion), in contrast to detecting bound entanglement, i.e.
View Article and Find Full Text PDFCharged lepton system symmetry under combined charge, parity, and time-reversal transformation (CPT) remains scarcely tested. Despite stringent quantum-electrodynamic limits, discrepancies in predictions for the electron-positron bound state (positronium atom) motivate further investigation, including fundamental symmetry tests. While CPT noninvariance effects could be manifested in non-vanishing angular correlations between final-state photons and spin of annihilating positronium, measurements were previously limited by knowledge of the latter.
View Article and Find Full Text PDFWe perform a parametric study of the newly developed time-of-flight (TOF) image reconstruction algorithm, proposed for the real-time imaging in total-body Jagiellonian PET (J-PET) scanners. The asymmetric 3D filtering kernel is applied at each most likely position of electron-positron annihilation, estimated from the emissions of back-to-back γ-photons. The optimisation of its parameters is studied using Monte Carlo simulations of a 1-mm spherical source, NEMA IEC and XCAT phantoms inside the ideal J-PET scanner.
View Article and Find Full Text PDFThe purpose of the presented research is estimation of the performance characteristics of the economic total-body Jagiellonian-PET system (TB-J-PET) constructed from plastic scintillators. The characteristics are estimated according to the NEMA NU-2-2018 standards utilizing the GATE package. The simulated detector consists of 24 modules, each built out of 32 plastic scintillator strips (each with cross section of 6 mm times 30 mm and length of 140 or 200 cm) arranged in two layers in regular 24-sided polygon circumscribing a circle with the diameter of 78.
View Article and Find Full Text PDFIn this paper we introduce a semi-analytic algorithm for 3-dimensional image reconstruction for positron emission tomography (PET). The method consists of the back-projection of the acquired data into the most likely image voxel according to time-of-flight (TOF) information, followed by the filtering step in the image space using an iterative optimization algorithm with a total variation (TV) regularization. TV regularization in image space is more computationally efficient than usual iterative optimization methods for PET reconstruction with full system matrix that use TV regularization.
View Article and Find Full Text PDFPurpose: The time-over-threshold (TOT) technique is being used widely due to itsimplications in developing the multi-channel readouts, mainly when fast signal processing is required. Using the TOT technique, as a measure of energy loss instead of charge integration methods, significantly reduces the signal readout costs by combining the time and energy information. Therefore, this approach can potentially be utilized in J-PET tomograph which is built from plastic scintillators characterized by fast light signals.
View Article and Find Full Text PDFWe present a quantum information theoretic version of the Klein-Nishina formula. This formulation singles out the quantity, the a priori visibility, that quantifies the ability to deduce the polarisation property of single photons. The Kraus-type structure allows a straightforward generalisation to the multiphoton cases, relevant in the decay of positronium which is utilized e.
View Article and Find Full Text PDFA detection system of the conventional PET tomograph is set-up to record data from [Formula: see text] annihilation into two photons with energy of 511 keV, and it gives information on the density distribution of a radiopharmaceutical in the body of the object. In this paper we explore the possibility of performing the three gamma photons imaging based on ortho-positronium annihilation, as well as the possibility of positronium mean lifetime imaging with the J-PET tomograph constructed from plastic scintillators. For this purposes simulations of the ortho-positronium formation and its annihilation into three photons were performed taking into account distributions of photons' momenta as predicted by the theory of quantum electrodynamics and the response of the J-PET tomograph.
View Article and Find Full Text PDFEur Phys J C Part Fields
November 2018
J-PET is a detector optimized for registration of photons from the electron-positron annihilation via plastic scintillators where photons interact predominantly via Compton scattering. Registration of both primary and scattered photons enables to determinate the linear polarization of the primary photon on the event by event basis with a certain probability. Here we present quantitative results on the feasibility of such polarization measurements of photons from the decay of positronium with the J-PET and explore the physical limitations for the resolution of the polarization determination of 511 keV photons via Compton scattering.
View Article and Find Full Text PDFIEEE Trans Med Imaging
November 2018
A novel approach to tomographic data processing has been developed and evaluated using the Jagiellonian positron emission tomography scanner as an example. We propose a system in which there is no need for powerful, local to the scanner processing facility, capable to reconstruct images on the fly. Instead, we introduce a field programmable gate array system-on-chip platform connected directly to data streams coming from the scanner, which can perform event building, filtering, coincidence search, and region-of-response reconstruction by the programmable logic and visualization by the integrated processors.
View Article and Find Full Text PDFA novel whole-body positron emission tomography (PET) system based on plastic scintillators is developed by the J-PET Collaboration. It consists of plastic scintillator strips arranged axially in the form of a cylinder, allowing the cost-effective construction of the total-body PET system. In order to determine the properties of the scanner prototype and optimize its geometry, advanced computer simulations were performed using the GATE (Geant4 application for tomographic emission) software.
View Article and Find Full Text PDFA novel plastic scintillator is developed for the application in the digital positron emission tomography (PET). The novelty of the concept lies in application of the 2-(4-styrylphenyl)benzoxazole as a wavelength shifter. The substance has not been used as scintillator dopant before.
View Article and Find Full Text PDFThe electron-positron annihilation into two photons is a standard technology in medicine to observe e.g. metabolic processes in human bodies.
View Article and Find Full Text PDFGreenberger-Horne-Zeilinger (GHZ) states and their mixtures exhibit fascinating properties. A complete basis of GHZ states can be constructed by properly choosing local basis rotations. We demonstrate this experimentally for the Hilbert space [Formula: see text] by entangling two photons in polarization and orbital angular momentum.
View Article and Find Full Text PDFIn this paper we estimate the time resolution of the J-PET scanner built from plastic scintillators. We incorporate the method of signal processing using the Tikhonov regularization framework and the kernel density estimation method. We obtain simple, closed-form analytical formulae for time resolution.
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