Effects of Spore Ratios on Fruiting Body Formation and Degeneration in the Heterothallic Fungus .

The medicinal mushroom is widely exploited in traditional medicine and nutraceuticals in Asian countries. However, fruiting body production in is facing degeneration through cultivation batches, and the molecular mechanism of this phenomenon remains unclear. This study showed that fruiting body formation in three different strains, namely G12, B12, and HQ1, severely declined after three successive culturing generations using the spore isolation method.