Publications by authors named "Hien S Franck"
Enhanced effect of seasonal malaria chemoprevention when coupled with nutrients supplementation for preventing malaria in children under 5 years old in Burkina Faso: a randomized open label trial.
Malar J
October 2023
Article Synopsis
- In rural Burkina Faso, a study was conducted to assess the impact of combining Seasonal Malaria Chemoprevention (SMC) with nutrient supplementation among undernourished children under five years old, due to high levels of both malaria and malnutrition in the area.
- The study involved 1059 children divided into three groups, each receiving different combinations of SMC and nutritional interventions, followed over a year to monitor malaria incidence and overall health through regular check-ups.
- Results showed that adding lipid-based nutrient supplements (PlumpyDoz) significantly reduced both uncomplicated malaria (by 23%) and severe malaria (by 52%) compared to the control group, also lowering general illness rates by 24%, while no effect was found on
Seasonal Malaria chemoprevention (SMC) is one of the large-scale life-saving malaria interventions initially recommended for the Sahel subregion, including Burkina Faso and recently extended to other parts of Africa. Initially, SMC was restricted to children 3 to 59 months old, but an extension to older children in some locations was recently recommended. Further characterization of SMC population profile beyond age criterion is necessary for understanding factors that could negatively impact the effectiveness of the intervention and to define complementary measures that could enhance its impact.
View Article and Find Full Text PDFImportance: Neonatal sepsis is a leading cause of neonatal mortality. New interventions are needed to decrease neonatal sepsis and mortality in regions with highest burden.
Objective: To evaluate the efficacy of intrapartum azithromycin to reduce neonatal sepsis or mortality, as well as neonatal and maternal infections.