Publications by authors named "Hiel Rutanhira"
Mol Oral Microbiol
February 2021
Article Synopsis
- Anti-sigma factors, including PG1659, regulate sigma factor expression in response to environmental stress, with PG1659 being cotranscribed with the rpoE gene, which is crucial for oxidative stress resistance in P. gingivalis.
- PG1659 is a hypothetical 130 amino acid transmembrane protein that has a calcium binding site and inhibits transcription initiation by the RpoE sigma factor.
- Studies showed that PG1659 interacts with RpoE, and its absence leads to significant upregulation of the rpoE gene, indicating PG1659's role as an anti-sigma factor in the bacteria's regulatory network.
