Magnesium absorption from mineral water decreases with increasing quantities of magnesium per serving in rats.

It is hypothesized that magnesium (Mg) absorption from mineral water is affected by the concentration of Mg in the water, the consumption pattern, and the volume consumed per serving. The present study examined the effect of serving volume and consumption pattern of artificial mineral water (AMW) and Mg concentration on Mg absorption in rats. Magnesium in AMW was labeled with magnesium-25 as a tracer.

Preventive effect of water containing magnesium ion on paw edema in adjuvant-induced arthritis rat.

We demonstrate the preventive effect of bittern water (BW), which enables the effective intake of magnesium ion (Mg(2+)), on paw edema in adjuvant-induced arthritis (AA) rat. BW (five kinds; BW-1, 2, 3, 4, 5) containing 10-200 mg/l Mg(2+) was used in this study. Arthritis was induced by the injection of 50 microl of a suspension of 10 mg/ml heat-killed butyricum (Mycobacterium butyricum) in Bayol F oil into the plantar region of the right hind foot and tail of rats.

Effects of magnesium content in the feed on cataract development in Shumiya cataract rat.

Cataract is a phenomenon in which the eye becomes opaque resulting in severe visual impairment, and senile cataract is the most common cause of blindness in the world. We investigated the effect of magnesium (Mg) supplementation on cataract development using shumiya cataract rat (SCR). The SCR were fed on either a low Mg (Mg 50 mg/kg), standard Mg (Mg 500 mg/kg), or high Mg (Mg 5000 mg/kg) diet from aged 5 to 15 weeks.

Delay of cataract development in the Shumiya cataract rat by the administration of drinking water containing high concentration of magnesium ion.

We discovered that the cataract development in the Shumiya cataract rat (SCR) can be prevented by the administration of deep-sea drinking water (DDW). A standard diet based on the American Institute of Nutrition guidelines (AIN-76) and DDW containing a high mineral concentration such as low, medium and high Mg2+ content (50, 200 and 1000 mg of Mg2+/l, respectively) were used in this study. SCRs were freely fed with combinations of the standard diet and purified water or DDW during 5-15 weeks of age.

Improvement of skin symptoms and mineral imbalance by drinking deep sea water in patients with atopic eczema/dermatitis syndrome (AEDS).

Deep sea water intake improves skin symptoms and mineral imbalance and decreases serum IgE levels mad IgE-inducing cytokines, IL-4, IL-13 and IL-18 in patients with atopic eczema/dermatitis syndrome (AEDS), while distilled water intake fails to do so.