Publications by authors named "Hidetetsu Hirokawa"

Article Synopsis
  • A multispecies outbreak of IMP-6 carbapenemase-producing Enterobacterales (IMP-6-CPE) occurred at a hospital in Japan, affecting 22 patients between July 2013 and March 2014.
  • The study used various molecular techniques to track the transmission of the bacteria and identified risk factors associated with acquiring IMP-6-CPE, particularly in patients undergoing specific surgical procedures.
  • Genomic analysis indicated the presence of a shared 50-kb plasmid across most samples, suggesting gene transfer between species and aiding in understanding how the outbreak spread among affected patients.
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Measles is a highly contagious infection caused by the measles virus (MV). This study performed long-term surveillance in order to survey the prevalence of MV. A total of 417 patients diagnosed with or suspected of having measles were tested for MV between January 2007 and December 2016 in Osaka City, Japan.

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Hand, foot, and mouth disease (HFMD) is an acute febrile illness characterized by fever; sore throat; and vesicular eruptions on the hands, feet, and oral mucosa. Until 2010, HFMD was predominantly associated with enterovirus (EV) A71 and coxsackievirus (CV) A16 in Japan. In 2011, CV-A6 emerged as a primary causative agent, causing the largest HFMD epidemic in Japan since 1981.

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[Objective] To contribute to countermeasures against pulmonary tuberculosis in patients with HIV infection through analyzing and evaluating its treatment outcomes and patient management. [Methods] The 'subjects were pulmonary tuberculosis patients newly registered between 2008 and 2014 in whom concomitant HIV infection was detected. For the control, sex- and generation-matched pulmonary tuberculosis patients newly registered in Osaka City -between 2012 and 2014 were adopted.

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Objectives: To examine and analyze the spread of measles in Osaka in 2014 and determine effective measures to prevent such occurrences.

Methods: We analyzed 47 cases of measles reported in Osaka, including one measles patient living in another prefecture where there was an outbreak. We focused on age distribution, the number of patients reported each week, estimated infection routes, history of measles vaccination, detection of viruses, and number of days it took to report the case after the onset of measles.

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