Iridocorneal contact as a potential cause of corneal decompensation following laser peripheral iridotomy.

Purpose: This study aimed to investigate the relationship between corneal decompensation following laser peripheral iridotomy (LPI) and iridocorneal endothelial contact.

Study Design: Retrospective observational case series.

Methods: Specular microscopy images of LPI recipients with narrow angles were taken at the central cornea and the 8 midperipheral corneal regions at approximately 3 mm from the center.

[Prone position ultrasound biomicroscopy for two plateau iris configuration cases with decreased corneal endothelial cells after laser iridotomy].

Background: To report a possibility of mechanical injury following laser iridotomy (LI) via the iris surface to the corneal endothelium possibly causing bullous keratopathy.

Case: Subjects were two patients with plateau iris configuration who had been given LI bilaterally. One eye of each patient showed serious decrease in cellular density of the corneal endothelium.

The relationship between the mean deviation slope and follow-up intraocular pressure in open-angle glaucoma patients.

Purpose: The purpose of this study was to analyze the relationship between the mean deviation (MD) slope as the progressive rate of visual field defects and the follow-up intraocular pressure (IOP) in open-angle glaucoma (OAG) patients.

Methods: This study was a retrospective, nonrandomized comparative study. A total of 287 eyes from 287 Japanese OAG patients were examined.

Assessment of the vision-specific quality of life using clustered visual field in glaucoma patients.

Purpose: To investigate the significance of vision-specific quality of life (QOL) in glaucoma patients based on the location of visual field defects.

Patients And Methods: We examined 336 eyes of 168 patients. The 25-item National Eye Institute Visual Function Questionnaire was used to evaluate patients' QOL.

Ocular hypotensive effects and safety over 3 months of switching from an unfixed combination to latanoprost 0.005%/timolol maleate 0.5% fixed combination.

Purpose: Latanoprost 0.005%/timolol maleate 0.5% combination eye drops are now available in Japan.

Evaluation of the relationship between quality of vision and the visual function index in Japanese glaucoma patients.

Background: We compared two types of visual field index including mean deviation (MD) and the visual field index (VFI) for assessing the relationship between quality of life (QOL) and the loss of visual field in open-angle glaucoma patients.

Methods: We examined 336 eyes of 168 consecutive glaucoma patients. All participants completed the Japanese version of the 25-item National Eye Institute Visual Function Questionnaire (NEI VFQ-25).

Evaluation of the relationship between quality of vision and visual function in Japanese glaucoma patients.

Purpose: To evaluate the correlation between quality of vision (QOV) and visual function in glaucoma patients.

Patients And Methods: The relationship between QOV and visual function was investigated in 200 Japanese glaucoma patients. QOV was assessed using the Japanese version of the 25-item National Eye Institute Visual Function Questionnaire.

Progression rate of total, and upper and lower visual field defects in open-angle glaucoma patients.

Purpose: We evaluated the progression rate of total, and upper and lower visual field defects in treated open-angle glaucoma patients.

Patients And Methods: This study was a retrospective, nonrandomized, comparative study. Five-hundred forty-four eyes from 315 Japanese open-angle glaucoma patients were examined.

Incidence, severity and factors related to drug-induced keratoepitheliopathy with glaucoma medications.

Purpose: To evaluate the incidence, severity, and factors related to drug-induced keratoepitheliopathy in eyes using antiglaucoma eye drops.

Patients And Methods: In a cross-sectional study, 749 eyes from 427 patients who had used one or more antiglaucoma eye drops were examined at Niigata University Medical and Dental Hospital or related facilities. The incidence and severity of superficial punctate keratitis (SPK), patient gender and age, type of glaucoma, and type of eye drops were recorded.

Tumor necrosis factor-alpha concentrations in the aqueous humor of patients with glaucoma.

Purpose: To investigate the concentration of tumor necrosis factor (TNF)-alpha in the aqueous humor of patients with glaucoma, including correlations with glaucoma subtypes and intraocular pressure.

Methods: The study population comprised 84 patients with open-angle glaucoma who were scheduled for filtration or cataract surgery. Glaucoma subgroups included 29 cases of primary open-angle glaucoma (POAG), 28 cases of normal-tension glaucoma (NTG), and 27 cases of exfoliation glaucoma (ExG).

Changes of scleral sulfated proteoglycans in three cases of nanophthalmos.

Purpose: To examine the composition of scleral sulfated proteoglycans in three nanophthalmic eyes by electron microscopic histochemistry.

Methods: Scleral tissues from three cases of nanophthalmos were collected from the Niigata University Hospital for transmission electron microscopic examination. Sulfated proteoglycans were studied using the cuprolinic blue (CB) dye binding method in conjunction with enzymatic digestion.

Oxidative stress markers in aqueous humor of patients with senile cataracts.

Purpose: To investigate the levels of oxidative stress markers in human eyes with senile cataracts.

Methods: We conducted a retrospective, case-controlled study of 57 patients with senile cataracts. To assess oxidative stress markers in the eye, we measured the enzymatic activities of superoxide dismutase (SOD) and catalase (CAT) as well as the total protein levels in aqueous humor.

[Visual course for proliferative diabetic retinopathy after pars plana vitrectomy].

Purpose: To investigate retrospectively the visual course for proliferative diabetic retinopathy after pars plana vitrectomy.

Cases And Methods: From January 2002 to December 2004, we operated 209 eyes with proliferative diabetic retinopathy. For this study, we selected 28 eyes in which the visual acuity could be followed for 6 months or longer after the vitrectomy.

[A case of acute angle-closure glaucoma secondary to annular ciliochoroidal detachment after unsutured cataract surgery].

Background: We report a patient with acute angle-closure glaucoma secondary to annular ciliochoroidal detachment after unsutured cataract surgery.

Case: An 82-year-old man was diagnosed with bilateral shallow central anterior chamber depth, flat peripheral anterior chamber, and elevated intraocular pressure. One day previously he had undergone uncomplicated unsutured cataract surgery in the right eye and eight days previously, in the left eye.