Biofabrication offers future hope for tackling various obstacles and challenges in tissue engineering and regenerative medicine: A Perspective.

Biofabrication is an emerging multidisciplinary field that makes a revolutionary impact on the researches on life science, biomedical engineering, and both basic and clinical medicine, has progressed tremendously over the past few years. Recently, there has been a big boom in three-dimensional (3D) printing or additive manufacturing (AM) research worldwide, and there is a significant increase not only in the number of researchers turning their attention to AM but also publications demonstrating the potential applications of 3D printing techniques in multiple fields. Biofabrication and bioprinting hold great promise for the innovation of engineering-based organ replacing medicine.

Three-dimensional inkjet biofabrication based on designed images.

Tissue engineering has been developed with the ultimate aim of manufacturing human organs, but success has been limited to only thin tissues and tissues with no significant structures. In order to construct more complicated tissues, we have developed a three-dimensional (3D) fabrication technology in which 3D structures are directly built up by layer-by-layer printing with living cells and several tissue components. We developed a custom-made inkjet printer specially designed for this purpose.

Usefulness of curry odorant of odor stick identification test for Japanese in olfactory impairment screening.

Conclusion: The curry odorant of the odor stick identification test for Japanese (OSIT-J) is useful in screening for olfactory impairment in Japanese subjects.

Objective: The present study was designed to determine the most useful odorant of the OSIT-J in screening for olfactory impairment in Japanese subjects.

Subjects And Methods: We studied olfactory impairment screening with the OSIT-J in 83 participants (49 male, 34 female; average age 50 years) in an executive check-up at NTT West Kanazawa Hospital.

Effects of cognitive factors on perceived odor intensity in adaptation/habituation processes: from 2 different odor presentation methods.

The purpose of this study, which comprised 2 experiments, was to investigate cognitive effects on odor perception. An odor was presented using an olfactometer. In Experiment 1 ("continuous" presentation), anethole, an odor unfamiliar to most Japanese individuals, was presented continuously for 1 session (20 min), whereas in Experiment 2 ("intermittent" presentation), odor stimuli were presented 60 times for a short duration (0.

A high-concentration NaCl solution does not stimulate the human trigeminal nerve at the tip of the tongue.

Conclusion: A 3 M NaCl solution does not stimulate the trigeminal nerve in the human tongue. Objectives. In rats, the trigeminal nerve has been reported to respond when the tongue is stimulated by a solution with an NaCl concentration of 0.