Publications by authors named "Hideki Egawa"
Cancer Diagn Progn
May 2024
Article Synopsis
- This study investigates risk factors for adverse events in patients with metastatic pancreatic cancer treated with a combination of nanoliposomal irinotecan, 5-fluorouracil, and L-leucovorin (nal-IRI/FL).
- It focuses on the UGT1A1 polymorphism, finding that patients with the homozygous variant (UGT1A1*6 or *28 (+/+)) experience lower white blood cell and neutrophil counts.
- Other identified risk factors for decreased white blood cell counts include high aspartate aminotransferase (AST) levels before therapy and being diagnosed with pancreatic head cancer.
