Publications by authors named "Hidekazu Nagasawa"

Article Synopsis
  • The study investigates the relationship between T values and protein levels in cerebrospinal fluid (CSF), focusing on verifying the effectiveness of Carr-Purcell-Meiboom-Gil (CPMG) pulses combined with non-negative least squares (NNLS) analysis to visualize these protein concentrations.
  • Researchers created albumin solutions with varying concentrations and used CPMG pulses to obtain T component values, which were then analyzed to assess changes in protein concentration in specific regions of interest.
  • Results showed that the method successfully distinguished between different albumin concentrations, producing color maps that indicated variations in T values, and demonstrated its clinical application by assessing protein levels in patients with cerebral conditions.
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Evaluation of chronic constipation is important, although it is often difficult to satisfactorily treat due to the complex interplay of factors. This study aimed to determine whether the volume of intraluminal contents and lateral diameter of the colon measured from computed tomography (CT) images were correlated with the symptoms of chronic constipation and stool consistency. Consecutive patients who underwent the Constipation Scoring System (CSS), Bristol Stool Form Scale (BSFS) questionnaires and simple abdominal CT were selected retrospectively.

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Objective: [F]Fluciclovine (anti-[F]FACBC) has demonstrated diagnostic efficacy for cancers of the brain where [F]fludeoxyglucose has limitations. We conducted a phase IIa study of anti-[F]FACBC to assess its accumulation pattern and safety in patients with malignant glioma.

Methods: Five patients with glioma scheduled for brain tumor resection received anti-[F]FACBC.

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Imaging start time of single-photon emission computed tomography (SPECT) scan is recommended between 3 hours and 6 hours after injection of ¹²³I-ioflupane in Ioflupane clinical practice guidelines. But image includes the effect of physiological actions of the human body and the attenuation at 13.27 hours physical half-life of ¹²³I.

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We encountered unexpected accumulation of thallium-201 in a patient with thalamic dementia resulting from bithalamic venous infarction induced by arteriovenous fistula in the posterior fossa The site and degree of abnormal accumulation varied between early and delayed thallium-201 SPECT images. This unexpected and complicated accumulation of thallium-201 appeared to depend on not only breakdown of the blood-brain barrier but also on the hemodynamics of this type of venous infarction.

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