Publications by authors named "Hidehiro Hayashi"

Article Synopsis
  • Endoscopic pancreatic stenting (EPS) is effective for treating pain in chronic pancreatitis, but there's limited understanding of why pain recurs after stent removal and no clear guidelines for when to remove stents.
  • A study of 95 patients who underwent EPS identified serum lipase level and pancreatic parenchymal thickness as key risk factors for pain recurrence after stent removal.
  • A prediction model based on these risk factors was developed, demonstrating good ability to predict pain recurrence which could aid in making informed decisions regarding pancreatic stent management.
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  • Sarcopenia, characterized by loss of skeletal muscle and reduced grip strength, is common in chronic pancreatitis (CP) patients, but the study explores their different impacts on health.
  • In the study of 102 CP patients, 55.9% had muscle loss, while 20.6% had reduced grip strength, revealing that muscle loss was linked to worse nutritional status and pancreatic function.
  • The findings suggest that muscle loss correlates with serious pancreatic issues like duct dilation and tissue atrophy, whereas reduced grip strength is more associated with older age and nutritional decline.
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Background: Urinary biopyrrin (UBP) is an oxidative metabolite formed from the reaction of bilirubin with reactive oxygen species. Previous studies have explored the relationship between UBP levels and certain diseases or pregnancy. However, UBP levels in healthy nonpregnant women have not been well examined.

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  • In Japan, type 1 autoimmune pancreatitis (AIP) is more common, while type 2 AIP is rare; this study focused on diagnosing type 2 AIP using endoscopic ultrasound-guided fine-needle aspiration and biopsy (EUS-FNAB).
  • The study analyzed tissue samples from 10 suspected type 2 AIP patients over nearly 12 years, revealing an 80% success rate in obtaining sufficient tissue volume.
  • Results showed that 40% of patients met the International Consensus Diagnostic Criteria level 1 for histological findings, while 50% met level 2, suggesting EUS-FNAB could be a viable alternative to more invasive procedures for type 2 AIP diagnosis.
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  • * A scoring system was developed based on factors like tumor size, vascularity, and Ki-67 index, achieving high accuracy for aggressive cases (AUC of 0.92).
  • * The system stratified patients into low, intermediate, and high-risk groups with corresponding ten-year survival rates of 100%, 90.9%, and 24.3%, respectively.
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Background: Biopyrrins are end products of oxidation reactions of bilirubin with reactive oxygen, and urinary biopyrrin (UBP) levels might increase under oxidative stress. The authors examined the reference UBP level for healthy adults and its physiological variation in 40 healthy volunteers recruited from among students of our university (20 students each from third-year and fourth-year), and compared the results with data on 8-hydroxy-2-deoxyguanosine (8OHdG).

Methods: UBP and 8OHdG levels could be considered as oxidative stress markers.

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Purpose: To retrospectively evaluate high-resolution computed tomography (HRCT) findings and clinical diagnoses of chronic interstitial pneumonia (IP) with a poor prognosis in young patients (≤50 years).

Materials And Methods: HRCT images of 8 men and 7 women (mean age 34.8 years) obtained before lung transplantation or autopsy were reviewed.

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During rice grain filling, grain moisture content and weight show dynamic changes. We focused on the expression of all 33 rice aquaporins in developing grains. Only two aquaporin genes, OsPIP2;1 and OsTIP3;1, were highly expressed in the period 10-25 days after heading (DAH).

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Cold acclimation process plays a vital role in the survival of chilling- and freezing-tolerant plants subjected to cold temperature stress. However, it remains elusive whether a cold acclimation process enhances root water uptake (a component of chilling tolerance) in chilling-sensitive crops such as rice. By analyzing the root hydraulic conductivity under cold stress for a prolonged time, we found that cold stress induced a gradual increase in root osmotic hydraulic conductivity [Lp(r(os))].

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Article Synopsis
  • The study examined how low air humidity and low root temperature (LRT) affect water uptake, growth, and aquaporin gene expression in rice plants.
  • Rice plants transpired 1.5- to 2-fold more in low humidity conditions, but LRT at 13°C further decreased transpiration and growth, especially under low humidity.
  • The research found that low humidity increased the expression of certain aquaporin genes, indicating that aquaporins may help rice plants adapt to these stress conditions.
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Root hydraulic conductivity (Lp(r)) and aquaporin amounts change diurnally. Previously, these changes were considered to be spontaneously driven by a circadian rhythm. Here, we evaluated the new hypothesis that diurnal changes could be triggered and enhanced by transpirational demand from shoots.

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Rapid growth of the submerged shoots of deepwater rice is essential for survival during the rainy season. We investigated changes in the expression of vacuolar H(+)-ATPase (V-ATPase), H(+)-pyrophosphatase (V-PPase), and aquaporins under submerged conditions. The amounts of vacuolar proton pumps, which support the active transport of ions into the vacuoles, were maintained on a membrane protein basis in the developing vacuoles.

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The two FLOWERING LOCUS T (FT)-like genes of apple (Malus x domestica Borkh.), MdFT1 and MdFT2, have been isolated and characterized. MdFT1 and MdFT2 were mapped, respectively, on distinct linkage groups (LGs) with partial homoeology, LG 12 and LG 4.

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Epidermoid cyst of the ovary is a very rare tumor. There have been only 21 case reports of it previously. We describe the computed tomography (CT) and magnetic resonance (MR) findings of 2 cases of ovarian epidermoid cyst.

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[HRCT of diffuse lung disease].

Nihon Igaku Hoshasen Gakkai Zasshi

January 2004

Article Synopsis
  • HRCT (High-Resolution Computed Tomography) is acknowledged as a valuable tool for assessing diffuse lung diseases, particularly in identifying ground-glass opacity (GGO) but has limitations in evaluating detailed lung tissue changes.
  • The author categorized GGO into four distinct patterns and emphasized its relevance in the context of interstitial pneumonia, alongside discussing the "crazy-paving appearance."
  • The study also compares the imaging capabilities of 0.5 mm HRCT with Multidetector CT and introduces advanced imaging techniques like micro-CT and synchrotron radiation CT for lung assessments.
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