Publications by authors named "Hideaki Nemoto"
Article Synopsis
- Transient lesions in the splenium of the corpus callosum (SCC) can occur after stopping certain antiepileptic drugs (AED), but the reasons for this are not fully understood.
- A case study of a schizophrenic patient who experienced a SCC lesion after discontinuing carbamazepine, an AED, revealed that the lesion coincided with the development of diabetes insipidus, which is linked to a lack of arginine-vasopressin (AVP).
- The findings suggest that stopping carbamazepine may lead to AVP deficiency, potentially contributing to the formation of transient SCC lesions.
We report the characteristics of three patients with spinocerebellar degeneration (SCD) with negative-type electroretinograms (ERGs). None of the patients showed retinal degeneration, but all had severe cerebellar ataxia, and brain MRIs showed cerebellar atrophy. Negative-type ERGs have been implicated in the selective functional impairment of the inner retinal layer, but few studies have reported dysfunction of the inner nuclear layer in SCD patients.
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