Publications by authors named "Hidde Overtoom"
Objective: To investigate whether prolonged time to surgery negatively affects survival, pathological outcome or postoperative complications in patients with histologically proven residual disease after neoadjuvant chemoradiotherapy for locally advanced esophageal cancer.
Summary Background Data: Historically, the standard time to surgery (TTS) has been six to eight weeks after completion of nCRT. The effect of prolonged TTS is gaining interest, with contradicting results on survival and surgical morbidity.
Article Synopsis
- Various anastomotic and reconstruction techniques were assessed in patients undergoing minimally invasive total (miTG) and distal gastrectomy (miDG) to understand their impact on postoperative complications.
- A study involving over 4,200 patients found that miTG had significantly higher rates of complications like anastomotic leakage and overall morbidity compared to miDG.
- The findings suggest that miDG is preferable for patients needing surgery, while linear stapled techniques should be favored in miTG to minimize risks.*
Objective: Locally advanced oesophageal squamous cell carcinoma can be treated with neoadjuvant chemoradiotherapy or chemotherapy followed by oesophagectomy. Discrepancies in pathological response rates have been reported between studies from Eastern versus Western countries. The aim of this study was to compare the pathological response to neoadjuvant chemoradiotherapy in Eastern versus Western countries.
View Article and Find Full Text PDFBackground: Long-term outcomes after rib fractures and the effect of treatment modality or chest wall injury severity on these outcomes remains uncertain. This retrospective cohort study evaluated the long-term pulmonary function, thoracic pain, and quality of life in patients admitted with rib fractures.
Methods: Patients admitted with rib fractures between January 1, 2012, and December 1, 2019, were included.