Introduction/aims: While amyotrophic lateral sclerosis (ALS) is primarily characterized as a motor system disorder, there is a growing body of evidence indicating sensory involvement. This study aimed to examine the hypothesis that somatosensory processing is impaired in ALS.
Methods: Study participants were ALS patients followed at the Neuromuscular Outpatient Unit, as well as healthy volunteers, from March 2021 to July 2023.
Introduction: In this study we explored brainstem reflex excitability changes, blink reflex recovery cycles (BRRCs), and masseter inhibitory reflexes (MIRs) in patients with amyotrophic lateral sclerosis (ALS).
Methods: Fourteen ALS patients and 14 healthy control subjects were recruited. The BRRC was examined at interstimulus intervals (ISIs) of 100, 200, 300, 400, 500, and 600 ms.
Clin Neurophysiol
September 2006
Objective: Assessment of the repetitive nerve stimulation (RNS) test parameters has some inherent difficulties, as too many co-dependent variables are involved. To circumvent these problems, we have employed the principal component analysis (PCA) for evaluating the RNS test.
Methods: We performed the RNS test on the abductor digiti quinti (ADQ), flexor carpi ulnaris (FCU) and orbicularis oculi (OO) muscles of 23 myasthenia gravis (MG) patients and 50 controls.