Publications by authors named "Hicham Elattar"
Arthritis is a debilitating condition impacting the quality of life for millions worldwide, characterized by pain and inflammation. Understanding the mechanisms of arthritis and developing effective treatments are crucial. This study investigated the hydroethanolic extract of Artemisia herba-alba for its protective potential against arthritis hallmarks, oxidative stress, and lipid peroxidation in vitro.
View Article and Find Full Text PDFEndocrine gland-derived vascular endothelial growth factor (EG-VEGF) and its receptor PROKR2 are associated to human colorectal cancer progression and peritoneal carcinomatosis.
Cancer Biomark
February 2018
Article Synopsis
- - The study investigates the role of endogenous vascular endothelial growth factor (EG-VEGF) in colorectal cancer (CRC) and its link to metastatic peritoneal carcinomatosis (PC), highlighting that high levels of circulating EG-VEGF are associated with advanced cancer stages.
- - Increased circulating levels of EG-VEGF were found in metastatic PC patients compared to those with CRC and healthy controls, and local EG-VEGF expression was linked to higher tumor and nodal stages in CRC.
- - The research suggests that the EG-VEGF and its receptors could play a key role in CRC's progression to PC and propose that circulating EG-VEGF might serve as a useful prognostic marker for CRC patients. *
Accurate measurement of Human epidermal growth factor receptor (HER2) gene expression is central for breast or stomach cancer therapy orientation and prognosis. The current standards testing methods for HER2 expression are immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH). In the current study, we explored the use of quantitative real time reverse transcription-PCR (RT-qPCR) as a potential method for the accurate relative quantification of the HER2 gene using formalin fixed paraffin embedded (FFPE) breast cancer biopsy samples.
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