Ga-DOTATOC-PET/MRI and C-5-HTP-PET/MRI are superior to Ga-DOTATOC-PET/CT for neuroendocrine tumour imaging.

The present study aimed to assess gadoxetate disodium contrast-enhanced (CE) positron emission tomography (PET)/magnetic resonance imaging (MRI) with Ga-DOTATOC and C-5-Hydroxy-tryptophan ( C-5-HTP) in comparison with iodine CE Ga-DOTATOC-PET/computed tomography (CT) for neuroendocrine tumour imaging. Detection rate and reader's confidence were evaluated for each separate image volume: CE-CT, CE-MRI including diffusion-weighted imaging, Ga-DOTATOC-PET performed at PET/CT, Ga-DOTATOC-PET performed at PET/MRI and C-5-HTP-PET, and for the three combined hybrid examinations Ga-DOTATOC-PET/MRI, C-5-HTP-PET/MRI and Ga-DOTATOC-PET/CT. In 11 patients, 255 lesions were depicted.