Publications by authors named "Hhoonisha Ramkalawan"
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Synopsis of recent research by authors named "Hhoonisha Ramkalawan"
- Hhoonisha Ramkalawan's research primarily focuses on the role of immune system components, particularly Toll-like receptors (TLRs) and PPARγ agonists, in autoimmune diseases such as Guillain-Barré syndrome and experimental autoimmune neuritis (EAN).
- One of her significant findings demonstrates that the PPARγ agonist pioglitazone has anti-inflammatory effects that can attenuate symptoms in EAN rats, suggesting a potential therapeutic application in autoimmune neuropathies.
- Additionally, her studies reveal that TLR2, TLR4, and TLR9 are expressed in patients with Guillain-Barré syndrome, expanding the understanding of innate immune responses in the disease, and indicate that inhibiting TLR9 could ameliorate clinical signs in EAN models.
