Extracellular vesicle-derived circHIPK3: Novel diagnostic biomarker for lung cancer.

Purpose: Lung cancer (LC) is a common malignancy worldwide. A great number of circular RNAs (circRNAs) have been identified that serve crucial roles in cancer development. Extracellular vesicles (EVs) and their contents have been shown to be biomarkers for the diagnosis and prognosis of LC.

Clinical and prognostic significance of in lung cancer.

Myosin heavy chain 11 (MYH11), encoded by the gene, is a protein that participates in muscle contraction through the hydrolysis of adenosine triphosphate. Although previous studies have demonstrated that gene expression levels are downregulated in several types of cancer, its expression levels have rarely been investigated in lung cancer. The present study aimed to explore the clinical significance and prognostic value of expression levels in lung cancer and to further study the underlying molecular mechanisms of the function of this gene.

-Asarone Increases Chemosensitivity by Inhibiting Tumor Glycolysis in Gastric Cancer.

-asarone is the main active ingredient of the Chinese herb which exhibits a wide range of biological activities. It was confirmed to be an efficient cytotoxic agent against gastroenteric cancer cells. However, the exact mechanism of -asarone in gastric cancer (GC) remains to be elucidated.

A clinical study of traditional Chinese medicine prolonging the survival of advanced gastric cancer patients by regulating the immunosuppressive cell population: A study protocol for a multicenter, randomized controlled trail.

Background: Gastric cancer (GC) is a common high-mortality disease, causing a serious social burden. Traditional Chinese medicine has been utilized to prevent and treat GC for many years but its effects remain unclear. The aim of our study is to elucidate the anti-tumor effects and the possible mechanism of Jianpi Yangzheng Xiaozheng decoction.