Study on the active ingredients of Shenghui decoction inhibiting acetylcholinesterase based on molecular docking and molecular dynamics simulation.

We aim to investigate the mechanism and effective components of Shenghui decoction (SHD), which has been shown to inhibit acetylcholinesterase (AChE) through molecular docking (MD) and molecular dynamics simulation (MDS). The effective ingredients in SHD were collected through the TCMSP database and literature review. All components were docked with AChE using CDOCKER.

Association of serum water-soluble vitamin exposures with the risk of metabolic syndrome: results from NHANES 2003-2006.

Introduction: Existing evidence suggests an association between certain vitamins and metabolic syndrome (MetS), but few epidemiological studies have focused on the effects of multivitamin co-exposure on MetS. This study aims to investigate the associations of the individual or multiple water-soluble vitamins (i.e.

Outage Performance Analysis of NOMA in Wireless Powered Cognitive Radio Networks with AF and DF Relaying Techniques.

Improving spectral efficiency under a certain energy limitation is an important design metric for future wireless communications as a response to the growing transmission demand of wireless devices. In order to improve spectral efficiency for communication systems without increasing energy consumption, this paper considers a non-orthogonal multiple access (NOMA)-based cognitive radio network, with the assistance of a wireless-powered relay station (RS), and then analyzes the system outage performance under amplified-and-forward (AF) and decoded-and-forward (DF) cooperative transmission modes. Specifically, the base station (BS) has the opportunity to cooperate by transmitting information through the RS, depending on whether the RS can harvest sufficient RF energy for cooperative transmission.

Bushen-Huatan-Yizhi formula reduces spatial learning and memory challenges through inhibition of the GSK-3β/CREB pathway in AD-like model rats.

Background: There is an increase in cases of Alzheimer's disease (AD) stemming from a globally ageing population demographic. Although substantial research efforts were performed for the scope of prophylaxis and therapeutic measure development against AD, based on its pathogenesis, most were unsuccessful. Bushen-Huatan-Yizhi formula (BSHTYZ) is extensively implemented to manage dementia.

Suan-Zao-Ren Decoction ameliorates synaptic plasticity through inhibition of the Aβ deposition and JAK2/STAT3 signaling pathway in AD model of APP/PS1 transgenic mice.

Background: Suan-Zao-Ren Decoction (SZRD) has been widely used to treat neurological illnesses, including dementia, insomnia and depression. However, the mechanisms underlying SZRD's improvement in cognitive function remain unclear. In this study, we examined SZRD's effect on APP/PS1 transgenic mice and mechanisms associated with SZRD's action in alleviating neuroinflammation and improving synaptic plasticity.

Efficacy and safety of ginkgo preparation in patients with vascular dementia: A protocol for systematic review and meta-analysis.

Background: Vascular dementia has become the second most common type of dementia after Alzheimer disease. At present, there is no uniform standard for VaD treatment guidelines among countries. The efficacy of ginkgo biloba in the treatment of vascular dementia is still controversial.

Efficacy and safety of acupuncture combined with western medicine for anxiety: A systematic review protocol.

Background: As a common clinical mental disorder, the prevalence rate of anxiety disorder increased yearly, devastating both physical health and social-economic prospect. The most common treatment relied on the use of western medications which is yet to fulfill ideal performance. While acupuncture is adopted as a treatment for anxiety disorders, the combination treatment of acupuncture and western medicines becomes more acknowledged.

Efficacy and safety of TCM Yangxin Anshen Therapy for insomnia: A systematic review and meta-analysis.

Background: Traditional Chinese Medicine (TCM) has gradually drawn the attention of clinicians as an alternative choice for insomniacs and TCM Yangxin Anshen Therapy (TYAT) is a crucial therapy of treating insomniacs. The purpose of this study was to evaluate the efficacy and safety of TYAT for insomnia.

Methods: Seven electronic databases were searched from inception to July 2019.

Hypergraph-Induced Convolutional Networks for Visual Classification.

At present, convolutional neural networks (CNNs) have become popular in visual classification tasks because of their superior performance. However, CNN-based methods do not consider the correlation of visual data to be classified. Recently, graph convolutional networks (GCNs) have mitigated this problem by modeling the pairwise relationship in visual data.

Task and Participant Scheduling of Trading Platforms in Vehicular Participatory Sensing Networks.

The vehicular participatory sensing network (VPSN) is now becoming more and more prevalent, and additionally has shown its great potential in various applications. A general VPSN consists of many tasks from task, publishers, trading platforms and a crowd of participants. Some literature treats publishers and the trading platform as a whole, which is impractical since they are two independent economic entities with respective purposes.