Publications by authors named "Heyou Zhou"
Expert Opin Biol Ther
December 2023
Article Synopsis
- - Solid tumors are increasingly common in various age groups and are often linked to high levels of cMET expression, complicating treatment due to the tumor's complexity and interconnected pathways.
- - The study introduces cMET-targeting Fab drug conjugates (FDCs), which combine a Fab fragment with a cytotoxic drug, investigated through both in vitro and in vivo testing.
- - FDCs show significant anti-tumor effectiveness against cMET-overexpressing cancer cells and human gastric tumors in mouse models, suggesting a promising new approach for treating solid tumors.
