The Exosome and its Application in Skin Wound Healing: A Systematic Review on In vitro Studies.

Background: Wound healing is a complex procedure frequently delayed in patients with underlying chronic conditions. Despite essential advances in tissue engineering and regenerative medicine, wound healing remains challenging, warranting novel methods for promoting wound healing. It has been demonstrated that exosomes are one of the main secretory products of different cell types, such as Mesenchymal Stem Cells (MSCs), for regulating various biological processes, including wound healing.

An efficient discrete Chebyshev polynomials strategy for tempered time fractional nonlinear Schrödinger problems.

Introduction: An interesting type of fractional derivatives that has received widespread attention in recent years is the tempered fractional derivatives. These fractional derivatives are a generalization of the well-known fractional derivatives, such as Caputo and Riemann-Liouville. In fact, these derivatives are obtained by multiplying the expressed fractional derivatives by an exponential factor.

Comparative Study of the Effects of Clonidine and Tranexamic Acid on Intraoperative Bleeding in Rhinoplasty: A Clinical Trial.

Introduction: The present study was conducted to compare the effects of clonidine and tranexamic acid on the volume of bleeding and quality of the surgical field in terms of bleeding in candidates who underwent rhinoplasty.

Methods: In this two-sided clinical trial, candidates eligible for rhinoplasty were randomly assigned to two treatment groups: tranexamic acid and clonidine. The first group received tranexamic acid at a dose of 700 µg/kg of body weight 2 hours before the surgical procedure, whereas the second group received clonidine orally at a dose of 2 mg/kg of body weight, 90 minutes before surgery.

Psychometric evaluation of the perfectionism scale's characteristics regarding physical appearance in patients seeking rhinoplasty surgery.

Introduction: This study aimed to investigate the psychometric characteristics of the perfectionism scale regarding physical appearance in patients seeking rhinoplasty.

Methods: This cross-sectional study involved 250 individuals seeking rhinoplasty in Kermanshah beauty clinics. Participants were purposively selected.

Determinants of unmet needs for mental health services amongst adolescents in Shiraz, Iran: a cross-sectional study.

Background: Mental disorders are increasingly prevalent among adolescents without appropriate response. There are a variety of reasons for unmet mental health needs, including attitudinal and structural barriers. Accordingly, we investigated perceived mental health needs, using mental health services, and their barriers in adolescents.

Contribution of obesity to racial and ethnic disparities in the risk of fetal myelomeningocele: a population-based study.

Background: Prepregnancy obesity and racial-ethnic disparities has been shown to be associated with meningomyelocele.

Objective: This study aimed to investigate the association of maternal periconceptional factors, including race-ethnicity and prepregnancy body mass index, with the prevalence of isolated fetal myelomeningocele.

Methods: This was a population-based cross-sectional study using Centers for Disease Control and Prevention birth data from 2016 to 2021.

Comparison of Six-strand and Four-strand Techniques on the Repair of Injured Deep Flexor Tendons of Zone II of the Hand: A Randomized Controlled Clinical Trial.

Background: Hand zone II flexor tendon repair had been associated with many complications thereby it was previously called no man's land. Although there is some agreement on the primary repair of flexor tendons in this area, it is challenging due to certain complications. We compared the six and four-strand techniques in the repair of flexor digitorum profundus (FDP) tendons of zone II.

Design, development and evaluation of a mobile-based self-care application for patients with COVID-19 not requiring hospitalization; a study of Northwest of Iran.

Background: Given the effective role of a mobile applications in disease management, disease monitoring, and self-care in patients with COVID-19 disease, we aimed to design, development and evaluation of a self-care Mobile app for COVID-19 patients not requiring hospitalization.

Methods: The design, development and evaluation the usability of the self-care and education mobile app for patients with COVID-19 disease were conducted in two main phases at 2021 in Northwest of IRAN; (1) Determine the features and capabilities and (2) Design, development and evaluation of self-care mobile App. JAVA programming languages and Android Operating System were used and selected to design and development of a mobile app.

A Systematic Literature Review on the Association Between Toxic and Essential Trace Elements and the Risk of Orofacial Clefts in Infants.

Orofacial clefts (OFCs) have been linked to various toxic and essential trace elements (TETEs) worldwide. However, review estimation is absent. Therefore, addressing the hypothesis that TETEs are associated with OFCs is the main area of this review.

Broadband high-efficiency 3-bit coding metasurface in transmission mode based on the polarization conversion technique.

The main drawback of the transmissive focusing metasurface (TFM) is its low operational bandwidth and aperture efficiency. Increasing both of these radiation characteristics simultaneously is a major challenge for these structures. This paper introduces a novel multi-state coding metasurface that utilizes system-level and element-level synthesis approaches to enhance frequency bandwidth and aperture efficiency.

Assessment of virtual education during the covid-19 pandemic from the perspective of faculty members and students: a cross-sectional descriptive study in northwest Iran.

Background: Since the coronavirus outbreak, many countries have replaced traditional education with virtual education in order to prevent the disease spread, and also avoid stopping education. The aim of the present study was to assess the virtual education status at Khalkhal University of Medical Sciences during the covid-19 pandemic from the perspective of students and faculty members.

Methods: This is a descriptive-cross-sectional study that was conducted between December 2021and February 2022.

Telemedicine technologies and applications in the era of COVID-19 pandemic: A systematic review.

Introduction: Telemedicine services saw substantial surges in their use during the COVID-19 pandemic due to the lockdowns and characteristics of the pandemic. Therefore, the authors aimed to systematically review the telemedicine services provided during the COVID-19 pandemic and their potential applications.

Methods: The authors searched PubMed, Scopus, and Cochrane databases on September 14, 2021.

Public Health Risk Evaluation through Mathematical Optimization in the Process of PPPs.

The public sector is becoming increasingly appealing. In the context of declining public money to support health studies and public health interventions, public-private partnerships with entities (including government agencies and scientific research institutes) are becoming increasingly important. When forming this type of cooperation, the participants highlight synergies between the private partners and the public's missions or goals.

Orthonormal piecewise Vieta-Lucas functions for the numerical solution of the one- and two-dimensional piecewise fractional Galilei invariant advection-diffusion equations.

Introduction: Recently, a new family of fractional derivatives called the piecewise fractional derivatives has been introduced, arguing that for some problems, each of the classical fractional derivatives may not be able to provide an accurate statement of the consideration problem alone. In defining this kind of derivatives, several types of fractional derivatives can be used simultaneously.

Objectives: This study introduces a new kind of piecewise fractional derivative by employing the Caputo type distributed-order fractional derivative and ABC fractional derivative.

Design, development, and evaluation of a registry system for hyperbaric oxygen therapy: A methodological study.

Background And Aims: Hyperbaric oxygen therapy (HBOT), utilizes 100% oxygen at pressures greater than sea-level atmospheric pressure, for the treatment of conditions in which the tissues starve for oxygen. The Undersea and Hyperbaric Medical Society (UHMS) has granted HBOT approval for the treatment of various conditions. On the other hand, applying informatics registry systems can improve care delivery, ameliorate outcomes, and reduce the costs and medical errors for the patients receiving HBOT treatment.

The evaluation of the relationship between Helicobacter pylori infection and frequency of postoperative complications of laparoscopic sleeve gastrectomy in Shahid Bahonar Hospital in Kerman between 2018 and 2020; a cross-sectional study.

Introduction: Among the bariatric surgery procedures, laparoscopic sleeve gastrectomy (LSG) is one of the most common methods for effective and permanent weight loss among patients with severe obesity. Nonetheless, the LSG can be associated with long-term and short-term complications for the patient. The present study is aimed to investigate the effect of Helicobacter pylori on the complications of LSG, to answer the question of whether eradication of Helicobacter pylori in patients undergoing surgery can be effective in reducing postoperative complications.

In vitro study of the mesenchymal stem cells-conditional media role in skin wound healing process: A systematic review.

Mesenchymal stromal cell (MSC)-conditioned medium (CM) offers a potential opportunity in the skin wound healing treatment. In this systematic review, an overview of the knowledge on this topic has been provided. A multistep search of the PubMed, Scopus and Science Direct database has been performed to identify papers on MSCs-conditional media used in skin wound healing.

Association of IL-22 and IL-22RA1 gene variants in Iranian patients with colorectal cancer.

Aim: In the current study, it was hypothesized that single nucleotide polymorphisms (SNPs) in the regulatory region of the IL-22 signaling pathway genes, including IL-22 and IL-22RA1 variants, may be associated with CRC susceptibility.

Background: The important role of pro-inflammatory cytokines during tumorigenesis is well-established. In recent years, IL-22 has been linked with colorectal cancer (CRC) through a number of mechanistic and observational studies.

Identifying data elements and key features of a mobile-based self-care application for patients with COVID-19 in Iran.

Mobile Health applications have shown different usages in the COVID-19 pandemic, which consisted of empowering patient's awareness, promoting patient's self-care, and self-monitor behaviors. The purpose of this study is to identify key features and capabilities of a mobile-based application for self-care and self-management of people with COVID-19 disease. This study was a descriptive-analytical study that was conducted in two main phases in 2020.

Mobile applications in HIV self-management: A systematic review of scientific literature.

Self-management through mHealth by mobile apps creates new opportunities for people living with HIV (PLHIV) for integrated and accurate management. Our study focused on current evidence on HIV selfmanagement mobile applications to identify and assess their objective, infrastructure, and target populations. A systematic review was conducted on studies that use apps to improve self-management among HIV-positive patients, using PubMed, Scopus, Embase, Science direct, UpToDate, and Web of Science databases.

How to Manage Red Alert in Emergency and Disaster Unit in the Hospital? Evidence From London.

This research gave an overview of coordinated hospital planning issues. In these issues, patients desire an arrangement for different source types, ideally as quickly as time permits. This field of context has just picked up academic interest, despite its reality since 1995.

Security challenges and solutions using healthcare cloud computing.

Cloud computing is among the most beneficial solutions to digital problems. Security is one of the focal issues in cloud computing technology, and this study aims at investigating security issues of cloud computing and their probable solutions. A systematic review was performed using Scopus, Pubmed, Science Direct, and Web of Science databases.

Vaccines for COVID-19: A Systematic Review of Feasibility and Effectiveness.

Introduction: Many potential vaccines for COVID-19 are being studied and developed. Several studies have reported on the safety and efficacy of these vaccines. This systematic review aimed to report on the current evidence concerning the feasibility and effectiveness of vaccines for COVID-19.

Genetic susceptibility of COVID-19: a systematic review of current evidence.

Introduction: While COVID-19 pandemic continues to spread worldwide, researchers have linked patterns of traits to poor disease outcomes. Risk factors for COVID-19 include asthma, elderly age, being pregnant, having any underlying diseases such as cardiovascular disease, diabetes, obesity, and experiencing lifelong systemic racism. Recently, connections to certain genes have also been found, although the susceptibility has not yet been established.

Design and Development of a Mobile-Based Self-Care Application for Patients with Type 2 Diabetes.

Introduction: Mobile-based applications play a leading role in changes in life-style, improve medication adherence, and provide a unique opportunity to aid patients with type 2 diabetes mellitus (T2DM) elevate their healthcare level. Therefore, we aim to design and develop a mobile-based self-care application for patients with T2DM.

Methods: The present study was an applied and developmental study to design and develop a mobile-based self-care application for people living with T2DM conducted in 2020.