Apatite textural and geochemical insights into the petrogenesis of intrusive rocks.

Apatite is widely used as an indicator mineral to reflect the characteristics and petrogenesis of host magma. In this study, we present apatite geochemical and in-situ Sr-Nd isotopic data of monzogranite, granodiorite and dioritic enclave in the eastern Songnen-Zhangguangcai Range Massif, aiming to fingerprinting their petrogenesis and magmatic evolution processes. Based on apatite textures and geochemistry characteristics, the apatites were categorized into two distinct groups.

Modulating Room-Temperature Phosphorescence of Phenothiazine Dioxide via External Heavy Atoms.

Developing pure organic materials with ultralong lifetimes and balanced quantum efficiency is attractive but challenging. In this study, we propose a novel strategy to investigate external heavy atoms by linking molecular emitters with halogen through a flexible alkyl chain. X-ray crystal analysis clearly reveal the halogen C-X-π interactions, which can be tuned by halogen donors, as well as the distance and geometry between them.

Productive scientists are associated with lower disruption in scientific publishing.

While scientific researchers often aim for high productivity, prioritizing the quantity of publications may come at the cost of time and effort dedicated to individual research. It is thus important to examine the relationship between productivity and disruption for individual researchers. Here, we show that with the increase in the number of published papers, the average citation per paper will be higher yet the mean disruption of papers will be lower.

Equirectangular Image Data Detection, Segmentation and Classification of Varying Sized Traffic Signs: A Comparison of Deep Learning Methods.

There are known limitations in mobile omnidirectional camera systems with an equirectangular projection in the wild, such as momentum-caused object distortion within images, partial occlusion and the effects of environmental settings. The localization, instance segmentation and classification of traffic signs from image data is of significant importance to applications such as Traffic Sign Detection and Recognition (TSDR) and Advanced Driver Assistance Systems (ADAS). Works show the efficacy of using state-of-the-art deep pixel-wise methods for this task yet rely on the input of classical landscape image data, automatic camera focus and collection in ideal weather settings, which does not accurately represent the application of technologies in the wild.

MicroRNA-1269 is downregulated in glioblastoma and its maturation is regulated by long non-coding RNA SLC16A1 Antisense RNA 1.

MicroRNA-1269 (miR-1296) promotes esophageal cancer. However, its role in other cancers, such as glioblastoma (GBM) is unclear. We predicted that miR-1269 might interact with long non-coding RNA (lncRNA) SLC16A1 Antisense RNA 1 (SLC16A1-AS1), a critical player in GBM.

Dark-field tomography of an attenuating object using intrinsic x-ray speckle tracking.

We investigate how an intrinsic speckle tracking approach to speckle-based x-ray imaging is used to extract an object's effective dark-field (DF) signal, which is capable of providing object information in three dimensions. The effective DF signal was extracted using a Fokker-Planck type formalism, which models the deformations of illuminating reference beam speckles due to both coherent and diffusive scatter from the sample. Here, we assumed that (a) small-angle scattering fans at the exit surface of the sample are rotationally symmetric and (b) the object has both attenuating and refractive properties.

Muricauda chongwuensis sp. nov., isolated from coastal seawater of China.

In the course of screening for bacterial predators, a Gram-stain-negative, non-flagellated, gliding, long rod-shaped, and yellow-pigmented bacterium, designated strain HICW, was isolated from coastal seawater of China. Phylogenetic analysis based on 16S rRNA gene sequences indicated that strain HICW represented a member of the genus Muricauda and showed the highest sequence similarity to M. aquimarina JCM11811 (98.

Systematic profiling of SARS-CoV-2-specific IgG responses elicited by an inactivated virus vaccine identifies peptides and proteins for predicting vaccination efficacy.

One of the best ways to control COVID-19 is vaccination. Among the various SARS-CoV-2 vaccines, inactivated virus vaccines have been widely applied in China and many other countries. To understand the underlying protective mechanism of these vaccines, it is necessary to systematically analyze the humoral responses that are triggered.

Size-dependent effects of polystyrene nanoplastics on autophagy response in human umbilical vein endothelial cells.

Ubiquitous nanoplastics (NPs) increase exposure risks to humans through the food chain and/or other ways. However, huge knowledge gaps exist regarding the fate and adverse impact of NPs on the human cardiovascular system. Autophagy is an important catabolic pathway that disposes of cytoplasmic waste through the lysosomes.

LncRNA SLC16A1-AS1 is Upregulated in Glioblastoma and Promotes Cancer Cell Proliferation by Regulating miR-149 Methylation.

Introduction: LncRNA SLC16A1-AS1 has been characterized as a critical player in lung cancer, while its role in glioblastoma (GBM) is unknown. By analyzing the TCGA dataset, we observed the upregulation of SLC16A1-AS1 expression in GBM. Therefore, we aimed to investigate the role of SLC16A1-AS1 in this cancer.

Quantitative material decomposition using linear iterative near-field phase retrieval dual-energy x-ray imaging.

This paper expands the linear iterative near-field phase retrieval (LIPR) formalism to achieve quantitative material thickness decomposition. Propagation-based phase contrast x-ray imaging with subsequent phase retrieval has been shown to improve the signal-to-noise ratio (SNR) by factors of up to hundreds compared to conventional x-ray imaging. This is a key step in biomedical imaging, where radiation exposure must be kept low without compromising the SNR.

Anti-Ageing Effect of Ethyl Acetate Layer on a d-galactose-Induced Mouse Model through the Reduction of Cellular Senescence and Oxidative Stress.

We aimed to study the effects of an ethyl acetate fraction of (PAE) on d-galactose (d-gal)-induced senescence and the underlying mechanism. Firstly, analysis of the phytochemical composition revealed total flavonoids, total phenolics, total saponins, rutin, and luteolin contents of 71.72 ± 2.

sp. nov., a novel prokaryotic predator isolated from coastal seawater of China.

Three prokaryotic predator strains, BL9, BL10 and BL28, were isolated with from coastal seawater of PR China. Cells of the strains were Gram-negative, vibrioid-shaped and motile with a single sheathed flagellum (25-28 nm wide). Cells were around 0.

Magainin-modified polydopamine nanoparticles for photothermal killing of bacteria at low temperature.

Photothermal therapy (PTT) is a promising method to kill bacteria because of the broad-spectrum of antibacterial activity and the ability of spatiotemporal regulation. In the previously reported systems, light induced high temperature (˜70 °C) was essential for effectively killing of bacteria, which, however, would also damage nearby nontarget cells or tissues. Here we report photothermal nanoparticles (NPs) for more targeting and killing bacteria at a relative low temperature.

Hydrofluoric acid-based etching effect on surface pit, crack, and scratch and laser damage site of fused silica optics.

In a large-scale, high-power laser facility, fused silica optics plays an irreplaceable role to transmit extremely intense lasers. However, the surface fractures, such as surface pit, crack, and scratch and laser damage site, of fused silica optics will shorten the lifetime of the optics and thus limit the output performance of the laser facility. In this work, besides experimental study, finite difference time domain (FDTD) simulation is performed to study hydrofluoric acid-based (HF-based) etching effect on the surface fractures.

Draft Genome Sequence of an Extracellular Protease-Producing Bacterium, VV6, Isolated from Arctic Seawater.

The draft genome sequence of the extracellular protease-producing bacterium VV6, isolated from Arctic seawater, was established. The genome size was approximately 4.365 Mb, with a G+C content of 66.

Linear iterative near-field phase retrieval (LIPR) for dual-energy x-ray imaging and material discrimination.

Near-field x-ray refraction (phase) contrast is unavoidable in many lab-based micro-CT imaging systems. Quantitative analysis of x-ray refraction (a.k.

Microvascular Decompression for Trigeminal Neuralgia Due to Venous Compression Alone.

Microvascular decompression (MVD) has been confirmed as an effective treatment of trigeminal neuralgia (TN); however, most previous reports just focused on MVD for TN caused by arterial conflict, there is a paucity of information about its use in venous compression causing TN. In the present study, the authors summarize 5-year experience of MVD for primary TN due to venous compression alone. Thirty-four patients with primary TN caused solely by veins underwent MVD.

Nobiletin inhibits invasion via inhibiting AKT/GSK3β/β-catenin signaling pathway in Slug-expressing glioma cells.

Epithelial-mesenchymal transition (EMT) is a pivotal event in tumor progression during which cancer cells undergo dramatic changes acquiring highly invasive properties. In this study, we found that nobiletin, a polymethoxylated flavone, suppressed migration and invasion in both U87 and U251 glioma cells. Expression of epithelial markers (E-cadherin and occludin) was upregulated; mesenchymal markers (N-cadherin, fibronectin) and the transcriptional factor Slug were downregulated after nobiletin treatment.

Impacts of mercury exposure on life history traits of Tigriopus japonicus: Multigeneration effects and recovery from pollution.

Here, through a multigenerational life-cycle test, Tigriopus japonicus were exposed to different mercuric chloride treatments in seawater (nominal concentrations of 0, 0.5, 1, 10, and 50μg/L) for five successive generations (F0-F4), and subsequently all the treatments were recovered in clean environments for one generation (F5). Six life history traits (survival, developmental time for nauplius phase, developmental time to maturation, fecundity, number of clutches, and number of nauplii/clutch) were examined for each generation.

[Isolation, identification and characterization of 68 protease-producing bacterial strains from the Arctic].

Objective: We screened and identified protease-producing bacterial strains from the Arctic, the results would help find cold-adapted protease.

Methods: In total 68 protease-producing strains were screened from the Arctic using the casein-agar plate under low temperature. All strains were classified using the 16S rRNA gene-restriction fragment length polymorphism (RFLP) and traditional phenotypic test.

[Composition and distribution of TCBS bacteria groups from sediments of Jiulong River estuary].

Objective: To investigate potential pathogens in waters of Xiamen from Jiulong River, and to provide useful information for the prevention and control of potential pathogen infections.

Methods: All samples were spread on Thiosulfate Citrate Bile Salts Sucrose (TCBS) agar plates, and then incubated at 26 +/- 1 degrees C for 24 +/- 2 h. In total 158 TCBS strains were isolated from TCBS agar plates and pure-cultivated on 2216E agar plates.