Effects of FB1 and HFB1 on Autonomous Exploratory and Spatial Memory and Learning Abilities in Mice.

Fumonisin B1 (FB1) is a representative form of fumonisin and is widely present in food and feed. Hydrolyzed fumonisin B1 (HFB1) emerges as a breakdown product of FB1, which is accompanied by FB1 alterations. While previous studies have primarily focused on the liver or kidney toxicity of FB1, with limited studies existing on its neurotoxicity and even fewer on the toxicity of HFB1, this study focuses on the neurotoxicity of FB1 and HFB1 exposure in mice investigated by the open field test, Morris water maze test, histopathological analysis, and nontargeted metabolomics.

Volatile Metabolite Profiling of Wheat Kernels Contaminated by .

Traditional methods used to detect fungi or mycotoxins are time-consuming and prevent real-time monitoring. In this study, solid-phase microextraction combined with full two-dimensional gas chromatography time-of-flight mass spectrometry was utilized to detect volatile organic compounds (VOCs) produced by fungi during grain infestation predictive PH-1 infestation in wheat. The results show that the VOCs emitted by can distinguish strains at different growth stages.