Publications by authors named "Hey-Ran Kim"

CD44 is a transmembrane receptor for hyaluronic acid. CD44 pre-mRNA contains 19 exons, 9 of which are alternatively spliced. Among the CD44 spliced variants, the v4-7 variant, one of the v6 exon-containing isoforms that contains variable exon 4, 5, 6 and 7, confers metastatic potential to non-metastatic cells.

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Article Synopsis
  • Spinal muscular atrophy (SMA) is caused by the deletion or mutation of the SMN1 gene, which is crucial for producing a protein important for spliceosome assembly.
  • The study investigates how specific splice site sequences in exons 7 and 8 of the SMN2 and SMN1 pre-mRNA affect splicing patterns.
  • Results indicate that while the 5' splice site of exon 7 enhances splicing of nearby exons, the 3' splice sites of exons 7 and 8 serve as enhancers for splice site selection instead of promoting nearby exon splicing.
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Rice (Oryza sativa L.) chromosome 3 is evolutionarily conserved across the cultivated cereals and shares large blocks of synteny with maize and sorghum, which diverged from rice more than 50 million years ago. To begin to completely understand this chromosome, we sequenced, finished, and annotated 36.

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