Publications by authors named "Hexuan Dong"
Article Synopsis
- * The study reveals that METTL3 influences m6A methylation, affecting cartilage extracellular matrix (ECM) degradation, and silencing METTL3 worsens the damage.
- * Cathepsin K (Ctsk) is identified as a key target in this process, and enhancing m6A levels through dietary methionine can reduce cartilage damage, suggesting a potential treatment strategy for KBD.
T-2 toxin is recognized as the most potent and prevalent secondary metabolite among monotrichous mycotoxins produced by Fusarium species. Multiple studies have substantiated the hepatotoxic effects of T-2 toxin. This study aimed to investigate whether NF-κB and NLRP3-mediated pyroptosis is involved in the underlying mechanism of T-2 toxin hepatotoxicity.
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