Publications by authors named "Heungkyu Park"

Article Synopsis
  • The increase in breast surgeries in Korea highlights the urgent need for accurate diagnosis of silicone breast implant complications like BIA-ALCL and BIA-SCC, as monitoring these issues is crucial for women's health.
  • A study analyzed 5,557 breast implants and found that 8.9% had ruptured, with subsequent surgeries confirming an agreement between ultrasound diagnoses and pathology results.
  • High-resolution ultrasonography proved to be an effective method for diagnosing these ruptures and understanding silicone migration, emphasizing the need for updating the current diagnostic classification system for better clinical outcomes.
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Purpose: Tumor markers such as carcinoembryonic antigen (CEA) and cancer antigen 15-3 (CA15-3) are widely used for monitoring breast cancer. However, the prognostic efficacy of preoperative elevations of CEA and CA15-3 levels in breast cancer patients remains controversial.

Methods: We retrospectively analyzed the clinicopathological parameters of 149,238 patients in the Korean Breast Cancer Society Registry Database who underwent surgery between January 2000 and December 2015.

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Background: Ovarian function suppression (OFS) has been shown to be effective as adjuvant endocrine therapy in premenopausal women with hormone receptor-positive breast cancer. However, it is currently unclear if addition of OFS to standard tamoxifen therapy after completion of adjuvant chemotherapy results in a survival benefit. In 2008, the Korean Breast Cancer Society Study Group initiated the ASTRRA randomized phase III trial to evaluate the efficacy of OFS in addition to standard tamoxifen treatment in hormone receptor-positive breast cancer patients who remain or regain premenopausal status after chemotherapy.

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The adenosine triphosphate-based chemotherapy response assay (ATP-CRA) has the advantages of standardization, evaluability, reproducibility, and accuracy, and can be performed on relatively small numbers of tumor cells. A total of 43 patients were enrolled in the present study, and chemosensitivity tests were successfully performed in 40 (93.0%) of these patients.

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