Publications by authors named "Heting Sun"
Article Synopsis
- Myocardial ischemia-reperfusion injury (MIRI) is caused by restoring blood flow to heart tissue, leading to issues like oxidative stress and inflammation.
- This study explores the effects of stachyose, a natural compound, on MIRI, finding that it improves heart function and reduces damage in models of the condition.
- Stachyose works by enhancing protective pathways in heart cells and suppressing inflammatory responses in immune cells, suggesting it could be a promising treatment option for MIRI that needs further research.
• The first complete genomic sequence of canine distemper virus from wild boar in northeast China was obtained. • Phylogenetic analysis showed that this wild boar CDV strain belongs to the Arctic lineage. • Wild boars in northeast China have detectable level of anti-CDV neutralizing antibodies, with a positive percentage of 18.
View Article and Find Full Text PDFAvian malaria is a vector-borne parasitic disease caused by Plasmodium infection transmitted to birds by mosquitoes. The aim of this systematic review was to analyze the global prevalence of malaria and risk factors associated with infection in wild birds. A systematic search of the databases CNKI, WanFang, VIP, PubMed, and ScienceDirect was performed from database inception to 24 February 2023.
View Article and Find Full Text PDFFour species of porcine circoviruses (PCV1-4) have been reported to circulate in Chinese domestic pigs, while the epizootiology of these viruses in free-ranging wild boars in China remains unknown. In this study, tissue and serum samples collected from diseased or apparently healthy wild boars between 2018 and 2020 in 19 regions of China were tested for the prevalence of PCV1-4 infections. Positive rates of PCV1, PCV2, and PCV3 DNA in the tissue samples of Chinese wild boars were 1.
View Article and Find Full Text PDFThe Prevalence of Rodents in China During Two Decades: A Systematic Review and Meta-Analysis.
Vector Borne Zoonotic Dis
December 2023
Article Synopsis
- Tsutsugamushi disease, caused by a zoonotic intracellular pathogen, has recently spread across China, especially north of the Yangtze River, raising public health concerns.
- A meta-analysis of 55 studies indicated that the overall infection rate of this pathogen in rodents is 5.5%, with a notable decline in prevalence after 2013, and highlighted specific rodent species that show higher infection rates.
- Seasonal changes affect rodent infection rates, peaking in autumn, and geographical factors such as temperature, altitude, precipitation, and humidity significantly influence infection probabilities, suggesting a need for preventive measures.
H10 subtype avian influenza viruses (AIVs) have been isolated from wild and domestic avian species worldwide and have occasionally crossed the species barrier to mammalian hosts. Fatal human cases of H10N8 infections and the recent detection of human H10N3 infections have drawn widespread public attention. In this study, 25 H10Nx viruses were isolated from wild waterfowl in China during a long-term surveillance of AIVs.
View Article and Find Full Text PDFTwo novel reassortant highly pathogenic avian influenza viruses (H5N1) clade 2.3.4.
View Article and Find Full Text PDFScabies is a common parasitic disease in many mammalian species, caused by the infestation of Sarcoptes scabiei. There is no consistent conclusion on whether Sarcoptes mites from different hosts or geographic locations have apparent genetic divergence. In this study, we collected and morphologically identified S.
View Article and Find Full Text PDFArticle Synopsis
- - The Ascaridoidea and Heterakoidea families are large parasites, and research has expanded our understanding of their diversity using mitochondrial genes, but evolutionary rates remain unclear.
- - This study analyzed ten complete mitogenome sequences from various subfamilies and found that Ascaridoidea splits into six distinct clades, with divergence occurring around 300-360 million years ago during the early Carboniferous Period.
- - The gene orders in Ascaridoidea are mostly conserved, while Heterakoidea shows significant genome rearrangement, mainly through a process known as tandem-duplication/random loss (TDRL), which provides insights into the evolutionary trends and genetic relationships among these species.
Genetic characterization of hepatitis E virus from wild boar in China.
Transbound Emerg Dis
September 2022
Article Synopsis
- This study focused on the prevalence of Hepatitis E virus (HEV) in wild boars across China, using advanced PCR techniques to analyze samples collected from 331 free-ranging boars over two years.* -
- The researchers found HEV RNA in 2.72% of liver samples, indicating infection in wild boars from eight different regions, with identified strains belonging to subtypes 4d, 4g, and 4h.* -
- Additionally, 28.2% of serum samples showed antibodies against HEV, marking this as the first detailed epidemiological report on HEV infections in China's wild boars, providing critical data for better control and prevention efforts.*
Article Synopsis
- In October 2020, 13 cases of a highly pathogenic strain of avian influenza A(H5N8) were found in wild ducks in Ningxia, China.
- These identified viruses were similar to H5N8 strains that were primarily present in European poultry earlier that year.
- Researchers also tracked the movement of the infected wild ducks and gathered evidence showing how the virus was spreading.
Article Synopsis
- Researchers isolated highly pathogenic avian influenza viruses H5N8 and H5N1 from migratory birds and fecal samples in Tibet, China, in May 2021.
- Phylogenetic analyses suggest the viruses may have spread from migratory birds' wintering grounds in South Asia, highlighting the complex interactions between different viral populations.
- The study emphasizes the need for increased surveillance of avian influenza in these regions and calls for stronger international collaboration to address potential outbreaks.
Molecular Detection of spp. and Infection in Wild Rodents From Six Provinces in China.
Front Cell Infect Microbiol
January 2022
Article Synopsis
- The study investigates the presence of zoonotic enteric pathogens in wild rodents across six provinces in China, specifically focusing on the prevalence of certain bacteria and their potential risk to human health.
- Out of 536 collected fecal samples, 11.6% tested positive for one pathogen and 3.4% for another, with varying prevalence rates across different regions.
- This research is significant as it confirms the existence of these pathogens in wild rodents and highlights their potential role as a source of human infection, offering new data on their distribution and genetic diversity.
Article Synopsis
- A 2-year study in Dandong, China, monitored influenza A viruses in migratory birds, isolating 27 viruses from various subtypes, including multiple samples of H7N4, indicating a potential public health risk.
- The novel reassortant influenza A(H7N4) virus was identified in both a woman and her poultry, showing varying virulence in mice, which raises concerns for other mammals, including humans.
- The study emphasizes the urgent need for ongoing surveillance of avian influenza in migratory birds and domestic poultry to manage public health threats, especially given the H7 subtype's ability to infect humans and increase pathogenicity.
Prevalence of spp. in Yaks () in China: A Systematic Review and Meta-Analysis.
Front Cell Infect Microbiol
November 2021
spp., the causative agent of cryptosporidiosis, can infect a variety of hosts. So far, there has been limited information regarding spp.
View Article and Find Full Text PDFis a protozoan that parasitizes the intestines. A number of hosts of have been found, including human and animals. However, there has been no research on the prevalence of in Tibetan antelope.
View Article and Find Full Text PDFPrevalence and Characterization of Species in Tibetan Antelope ().
Front Cell Infect Microbiol
October 2021
is an enteric parasite, which can infect multiple mammals including livestock and wildlife. Tibetan Antelope () is one of the most famous wildlife species, that belongs to the first class protected wild animals in China. However, it has not been known whether Tibetan Antelope is infected with so far.
View Article and Find Full Text PDFHelminth diseases have long been a threat to the health of humans and animals. Roundworms are important organisms for studying parasitic mechanisms, disease transmission and prevention. The study of parasites in the giant panda is of importance for understanding how roundworms adapt to the host.
View Article and Find Full Text PDFArticle Synopsis
- In October 2020, two dead swans in Inner Mongolia, China tested positive for highly pathogenic avian influenza A(H5N8).
- Genetic analysis indicated that these viruses belong to clade 2.3.4.4b.
- The isolates were found to be similar to H5N8 viruses that were also detected in Eurasia during the same fall of 2020.
The genus Orthonairovirus, which is part of the family Nairoviridae, includes the important tick-transmitted pathogens Crimean-Congo hemorrhagic fever virus and Nairobi sheep disease virus, as well as many other poorly characterized viruses found in ticks, birds and mammals. In this study, we identified a new orthonairovirus, Songling virus (SGLV), from patients who reported being bitten by ticks in Heilongjiang Province in northeastern China. SGLV shared similar genomic and morphological features with orthonairoviruses and phylogenetically formed a unique clade in Tamdy orthonairovirus of the Nairoviridae family.
View Article and Find Full Text PDFPrevalence and Genotyping of Infection in Raccoon Dogs () in Northern China.
Vector Borne Zoonotic Dis
March 2020
Article Synopsis
- A study was conducted in northern China to investigate the prevalence and genetic diversity of a protozoan parasite found in domestic raccoon dogs, focusing on three provinces: Jilin, Liaoning, and Hebei.
- Out of 337 tissue samples taken, 16 (4.75%) tested positive for the parasite using a specific nested PCR technique, with further genetic analysis identifying two distinct genotypes (ToxoDB Genotype #9 and #10).
- The findings indicate that ToxoDB Genotype #9 is likely a primary reservoir for the parasite, highlighting potential risks for human infection related to these domestic raccoon dogs.
Avian influenza viruses (AIVs) in wild birds pose a pandemic threat to humans and to the poultry industry. To assess AIV and AIV antibody prevalence in wild birds in China, a systematic review and meta-analysis were conducted. We searched PubMed, Google Scholar, Cochrane Library, Clinical Trial, VIP, CNKI, and WANFANG for published papers related to the prevalence of AIVs and their associated antibodies in wild birds in China from Mar.
View Article and Find Full Text PDFsubsp. is an important pathogen of goats that causes contagious caprine pleuropneumonia. Here, we report the complete genome sequence of subsp.
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