An examination of the "interpersonalness" of the outcome questionnaire.

This study examined whether the Outcome Questionnaire-45 (OQ) and its subscales assessed unique interpersonal distress. The Inventory of Interpersonal Problems (IIP) was used to assess discriminant validity for unique interpersonal distress. Participants (N = 121) were recruited from a southwestern university counselor training center.

Nocturnal periodic breathing during acclimatization at very high altitude at Mount Muztagh Ata (7,546 m).

Rationale: Quantitative data on ventilation during acclimatization at very high altitude are scant. Therefore, we monitored nocturnal ventilation and oxygen saturation in mountaineers ascending Mt. Muztagh Ata (7,546 m).

A descriptive study of the radiographic density of implant restorative cements.

Statement Of Problem: Cementation of implant prostheses is a common practice. Excess cement in the gingival sulcus may harm the periodontal tissues. Identification of the excess cement may be possible with the use of radiographs if the cement has sufficient radiopacity.

The ecological research needs of business.

Businesses have an unrivalled ability to mobilize human, physical and financial capital, often manage large land holdings, and draw on resources and supply products that impact a wide array of ecosystems. Businesses therefore have the potential to make a substantial contribution to arresting declines in biodiversity and ecosystem services. To realize this potential, businesses require support from researchers in applied ecology to inform how they measure and manage their impacts on, and opportunities presented to them by, biodiversity and ecosystem services.

Microfracture for chondral defects of the talus: maintenance of early results at midterm follow-up.

We determined whether the early improvement in symptoms and function after microfracture in the management of articular cartilage defects of the talus is maintained at mid term follow-up. Factors influencing outcome and postoperative magnetic resonance imaging were also evaluated. We performed data collection prospectively using the Hannover Scoring System for the ankle (HSS) and a Visual Analog Scale (VAS) for pain and function preoperatively, at 1 +/- 0.

A method for assaying perchlorate concentration in microbial cultures using the fluorescent dye resazurin.

Low concentrations (microg/L) of the perchlorate anion, ClO(4)(-), have been measured in surface and ground water supplies in many locations throughout the United States. Perchlorate is known to affect the function of the thyroid gland in mammals and its toxicity primarily results from its inhibition of thyroid hormone output. The major sources of perchlorate contamination in surface and ground waters are defense contractors, military installations, propellant manufacturers and agriculture.

Visual field deficits following anterior temporal lobectomy: long-term follow-up and prognostic implications.

Purpose: The aim of this study was to assess the incidence of mild (90 degrees from vertical) visual field defects (VFDs) in patients after anterior temporal lobectomy (ATL), and their postoperative improvement over time.

Methods: The angles of postoperative VFDs of 75 patients who underwent ATL were recorded at various time points (1, 2, 6, 12, 18, 24, and 36+ months).

Results: Of all 23 patients who came in for their <1 month postoperative appointment, 65% of patients had surgically induced VFDs <90 degrees , whereas 35% had VFDs >90 degrees postoperatively.

Development of drinking water standards for perchlorate in the United States.

Perchlorate, an anion that originates as a contaminant in ground and surface waters, is both naturally occurring and manmade. Because of its toxicity, there has been increased interest in setting drinking water safety standards and in health effects when perchlorate is present at low (parts per billion (ppb)) levels. In January 2009, the EPA issued a heath advisory to assist state and local officials in addressing local contamination of perchlorate in drinking water.

Aging and everyday judgments: the impact of motivational and processing resource factors.

It has been hypothesized that reductions in cognitive resources might result in older adults engaging in less systematic processing than young adults when making everyday judgments. In 2 experiments, the authors tested individuals aged from 24 to 89 years to examine the degree to which task-related information associated with more superficial versus complex processing differentially influenced performance. They also examined the hypothesis that motivational factors would moderate age differences in processing complexity.

Knowledge and attitudes about epilepsy: a survey of dentists in London, Ontario.

Background: The controversial relation between societal knowledge and attitudes about epilepsy may affect the access of people with epilepsy to dental care.

Materials And Methods: A questionnaire that evaluated knowledge about epilepsy, attitudes toward epilepsy and willingness to provide dental care to people with epilepsy was administered to all 288 dentists in the city of London, Ontario, Canada.

Results: Of the 197 respondents, 75.

Quantification of liver perfusion by dynamic magnetic resonance imaging: experimental evaluation and clinical pilot study.

Changes in liver microcirculation are considered essential in assessing ischemia-reperfusion injury, which in turn has an impact on liver graft function and outcome following liver transplantation (LTx). The aim of this study was to introduce dynamic magnetic resonance imaging (dMRI) as a new technique for overall quantification of hepatic microcirculation and compare it to perfusion measured by laser Doppler flowmetry (LDF; hepatic artery/portal vein) and thermal diffusion (TD). The study included 3 groups, measuring hepatic blood flow and microcirculation with the help of TD, LDF, and dMRI.

Task demands moderate stereotype threat effects on memory performance.

Previous research has demonstrated that older adults' memory performance is adversely affected by the explicit activation of negative stereotypes about aging. In this study, we examined the impact of stereotype threat on recognition memory, with specific interest in (a) the generalizability of previously observed effects, (b) the subjective experience of memory, and (c) the moderating effects of task demands. Older participants subjected to threat performed worse than did those in a nonthreat condition but only when performance constraints were high (i.

Aging and selective engagement: the moderating impact of motivation on older adults' resource utilization.

Two studies were conducted to examine age differences in the impact of motivation in a social cognitive task. We tested the hypothesis that aging is associated with an increase in the selective engagement of cognitive resources in support of performance. Different-aged adults read descriptions of 2 people in order to determine which was better suited for a particular job.

Effect of ascent protocol on acute mountain sickness and success at Muztagh Ata, 7546 m.

Bloch, Konrad E., Alexander J. Turk, Marco Maggiorini, Thomas Hess, Tobias Merz, Martina M.

Moderators of and mechanisms underlying stereotype threat effects on older adults' memory performance.

Recent research has suggested that negative stereotypes about aging may have a detrimental influence on older adults' memory performance. This study sought to determine whether stereotype-based influences were moderated by age, education, and concerns about being stigmatized. Possible mechanisms underlying these influences on memory performance were also explored.

Evaluation of Swiss guidelines for the indication for hysterectomy in relation to patient outcome.

Background: The application of national guidelines which specify the appropriateness for hysterectomy is believed to lead to improved patient outcomes. However, there was no evidence to support this assumption by outcome data.

Goals: To evaluate adherence to guidelines and the validity of the 1997 Swiss guidelines for the appropriateness of hysterectomy based on changes in patients' functional and psychosocial status.

BRAVO wireless 48 hour pH-metric system.

The monitoring pH exposition in the esophagus plays an important role in the diagnosis of gastro-esophageal reflux disease (GERD). Recently, a new wireless method for intraesophageal pH measurement called the BRAVO system has been introduced for clinical application. This wireless system provides data on pH exposure of the esophagus through a small capsule clipped at the oesophageal mucosa.

Age differences in dual information-processing modes: implications for cancer decision making.

Age differences in affective/experiential and deliberative processes have important theoretical implications for cancer decision making, as cancer is often a disease of older adulthood. The authors examined evidence for adult age differences in affective and deliberative information processes, reviewed the sparse evidence about age differences in decision making, and introduced how dual process theories and their findings might be applied to cancer decision making. Age-related declines in the efficiency of deliberative processes predict poorer-quality decisions as we age, particularly when decisions are unfamiliar and the information is numeric.

New insights into ocular blood flow at very high altitudes.

Little is known about the ocular and cerebral blood flow during exposure to increasingly hypoxic conditions at high altitudes. There is evidence that an increase in cerebral blood flow resulting from altered autoregulation constitutes a risk factor for acute mountain sickness (AMS) and high-altitude cerebral edema (HACE) by leading to capillary overperfusion and vasogenic cerebral edema. The retina represents the only part of the central nervous system where capillary blood flow is visible and can be measured by noninvasive means.

closo-borane conjugated regulatory peptides retain high biological affinity: synthesis of closo-borane conjugated Tyr(3)-octreotate derivatives for BNCT.

Despite the improvements in cancer therapy during the past years, high-grade gliomas and many other types of cancer are still extremely resistant to current forms of therapy. Boron neutron capture therapy (BNCT) provides a promising way to destroy cancer cells without damaging healthy tissue. However, BNCT in practice is still limited due to the lack of boron-containing compounds that selectively deliver boron to cancer cells.

Gadolinium-containing magnetic resonance imaging contrast and nephrogenic systemic fibrosis: a case-control study.

Background: Nephrogenic systemic fibrosis (NSF) is a newly described disorder occurring in persons with renal failure. Gadolinium-based contrast used in magnetic resonance imaging (MRI) has been suggested as a cause. A cluster of patients with NSF was investigated to identify risk factors.

[Quality control and quality of life after uterine fibroid embolization: long-term results].

This study was performed in order to evaluate the changes in uterine fibroid symptoms and their impact on the quality of life after uterine fibroid embolization (UFE). The patients source of information about this novel treatment and their reasons for choosing UFE were also studied. Health-related quality of life and the status of uterine fibroid symptoms were assessed in 44 patients before and after treatment using a validated questionnaire.

Dietary energy source affects glucose kinetics in trained Arabian geldings at rest and during endurance exercise.

Advances in modeling and tracer techniques provide new perspective into glucose utilization and potential consequences to health or exercise performance. This study used stable isotope and compartmental modeling to evaluate how adaptation to a feed high in sugar and starch (SS) compared with a feed high in fat and fiber (FF) affects glucose kinetics at rest and during exercise in horses. Six trained Arabians adapted to each feed underwent similar tests at rest and while running approximately 4 m/s on a treadmill.

Using a genetic algorithm to drive a microbial ecosystem in a desirable direction.

The functioning of natural microbial ecosystems is influenced by various biotic and abiotic conditions. The careful experimental manipulation of environmental conditions can drive microbial ecosystems toward exhibiting desirable types of functionality. Such manipulations can be systematically approached by viewing them as a combinatorial optimization problem, in which the optimal configuration of environmental conditions is sought.

Effects of simvastatin on cerebrospinal fluid biomarkers and cognition in middle-aged adults at risk for Alzheimer's disease.

Background: Statins reduce amyloid-beta (Abeta) levels in the brain and cerebrospinal fluid (CSF) in animals and may thereby favorably alter the pathobiology of AD. It is unclear if statins modify Abeta metabolism or improve cognition in asymptomatic middle-aged adults at increased risk for AD.

Methods: In a 4-month randomized, double-blind, controlled study, we evaluated the effects of simvastatin 40 mg daily vs.