Publications by authors named "Hesham Lasheen"
Article Synopsis
- The study aimed to evaluate the effectiveness and safety of budesonide, a steroid injection, for treating chronic rhinosinusitis with nasal polyps (CRSwNP) compared to oral steroids and a control group.
- In a randomized clinical trial with 150 patients, results showed that both budesonide and oral steroids significantly improved symptoms and nasal polyp scores, while the control group did not show significant improvement.
- The conclusion indicates that intrapolyp steroid injections, especially budesonide, are a safe and effective option for patients with recurrent nasal polyps, potentially reducing the need for systemic steroids.
Problem: To assess the efficacy of budesonide intrapolyp injection in chronic rhinosinusitis with nasal polyps.
Method: Ninety patients were divided into three groups; group A was given oral prednisolone, group B was given budesonide intrapolyp injection weekly for five consecutive weeks and group C was given budesonide as nasal irrigation for one month. Patients were assessed using Sino-Nasal Outcome Test 22 score, total nasal polyp score, serum immunoglobulin E, absolute eosinophilic count, and morning cortisol level before treatment, one week and three months after completing their treatment.