Betamethasone-enhanced vein graft conduit accelerates functional recovery in the rat sciatic nerve gap.

Purpose: The objective of the study was to assess the effect of topically administered betamethasone on peripheral nerve regeneration and functional recovery after sciatic nerve transection in the rat.

Materials And Methods: Forty-five healthy male white Wistar rats were divided into 3 experimental groups (n = 15), randomly. In the treatment group, a 10-mm sciatic nerve defect was bridged by use of an inside-out vein graft filled with 10 μL betamethasone (0.