Psychophysical changes after total sleep deprivation and experimental muscle pain.

Sleep disturbances exacerbate chronic pain, increase psychological load, and increase inflammation. Delayed onset muscle soreness (DOMS) mimics aspects of chronic pain, predominantly affecting peripheral pain mechanisms, while experimental sleep provocations have been shown to impact central pain mechanisms. This study aimed to combine a DOMS model with total sleep deprivation (TSD) to create a novel model affecting both peripheral and central pain mechanisms.

Investigation of pain sensitivity following 3 nights of disrupted sleep in healthy individuals.

Background: Poor quality sleep is a common complaint among people with chronic pain. The co-occurrence of poor sleep quality and chronic pain often comes with increased pain intensity, more disability and a higher cost of healthcare. Poor sleep has been suggested to affect measures of peripheral and central pain mechanisms.

Psychophysical predictors of experimental muscle pain intensity following fatiguing calf exercise.

Musculoskeletal pain affects approximately 20% of the population worldwide and represents one of the leading causes of global disability. As yet, precise mechanisms underlying the development of musculoskeletal pain and transition to chronicity remain unclear, though individual factors such as sleep quality, physical activity, affective state, pain catastrophizing and psychophysical pain sensitivity have all been suggested to be involved. This study aimed to investigate whether factors at baseline could predict musculoskeletal pain intensity to an experimental delayed onset of muscle soreness (DOMS) pain model.

Effect of question prompt lists for cancer patients on communication and mental health outcomes-A systematic review.

Objective: To provide a systematic review on the effects of question prompt lists (QPL) in oncological settings.

Methods: A systematic literature search was conducted in Medline, PsycINFO and the Cochrane Collaboration. Randomized controlled studies (RCTs) that evaluated QPL-only interventions were included.

Engaging patients in primary care design: An evaluation of a novel approach to codesigning care.

Objective: Recognition is growing that to create truly patient-centred care, health-care organizations need to partner with patients around care design. More research into the benefits of engaging patients and the most effective ways of partnering with them is needed.

Methods: This study assessed the process and impact of a collaborative effort to design a new clinic service that balanced the number of patient and clinical provider/staff codesigners involved and recruited patients to represent diverse perspectives.

The CardioMEMS system in the clinical management of end-stage heart failure patients: three case reports.

Background: Recent clinical trials have shown that pulmonary artery pressure-guided therapy via the CardioMEMS™ system reduces the risk of recurrent hospitalizations in chronic heart failure (HF) patients. The CardioMEMS™ pressure sensor is percutaneously implanted in a branch of the pulmonary artery and allows telemetric pressure monitoring via a receiver. According to the most recent ESC guidelines, this technology has currently a class IIb indication in patients with class III New York Heart Association symptoms and a previous hospitalization for congestive heart failure within the last year, regardless of ejection fraction.

Evaluation of the Learning to Integrate Neighborhoods and Clinical Care Project: Findings from Implementing a New Lay Role into Primary Care Teams to Address Social Determinants of Health.

Introduction: Health systems increasingly recognize the impact of social determinants of health such as access to housing, transportation, and nutritious food. Lay health workers have been used to address patients' social determinants of health through resource referral and goal setting in targeted populations, such as individuals with diabetes. However, we know of no studies that evaluate this type of role for a general primary care population.

A distinct subgroup of cardiomyopathy patients characterized by transcriptionally active cardiotropic erythrovirus and altered cardiac gene expression.

Recent studies have detected erythrovirus genomes in the hearts of cardiomyopathy and cardiac transplant patients. Assessment of the functional status of viruses may provide clinically important information beyond detection of the viral genomes. Here, we report transcriptional activation of cardiotropic erythrovirus to be associated with strongly altered myocardial gene expression in a distinct subgroup of cardiomyopathy patients.

[Closure of vesicovaginal fistulas from the urologic viewpoint with reference to endoscopic fibrin glue technique].

Indications and results of conventional operative closure of iatrogenic vesicovaginal fistulas (24 patients) and exclusively endoscopic fibrin sealing (6 patients) have been reported. The primary closure rate of the first mentioned method is 88 per cent, but 66 per cent in cases of endoscopic fibrin sealing. The last method is reported in detail.

Unilateral renal oncocytoma: a case report.

A case of unilateral renal oncocytoma is reported. Diagnosis, clinical features and management of the tumour are discussed in the light of international literature. The value of angionephrography in the diagnosis of the tumour and in the preoperative planning of surgical therapy is emphasized.

[Possibilities and significance of transarthroscopic operations].

This paper reports on a poll conducted among 80 patients one to seven months after transarthroscopic knee joint surgery.

[Functional and cosmetic results in thumb replacement surgery].

The operations to replace the thumb have been proved in thalidomide embryopathy both functionally and cosmetically. The best results are achieved in the pollicisation of dolichophalangeal triphalangeal thumbs. Simultaneously existing radial club hand impairs the operative results considerably.

[Biomechanical problems in acromio plasty of the shoulder joint (author's transl)].

In the confines of the spatium subacromiale, the anatomic structures are subjected to increased wear by friction and convolution. In case of compression syndromes relief is obtained by a partial resection of the acromion, by an acromio plasty, or by a complete removal of the acromion, i.e.

[Experience with percutaneous embolization of renal tumours (author's transl)].

We have repeated first observations of various authors of blocking angiography in 8 patients with renal tumours. Comparing angiographic findings and the surgical specimens, the success of embolization could be assessed. Control angiography 2 months following an inoperable renal tumor showed shrinking of the tumour by about one half and improvement of the general condition of the patient.