South Asians living in the United States are frequently underrepresented in health research. Their lack of participation limits the generalizability of research to them and keeps them from receiving the high-quality care and innovation that some studies may offer. "Research Ready" is a five-panel, community co-created graphic-style story that encourages discussion around the purpose of research, safety/protection while participating, and why diverse participation-including South Asians-improves study results and leads to more effective interventions/treatments.
View Article and Find Full Text PDFMany youths and young adults have variable environmental health knowledge, limited understanding of their local environment's impact on their health, and poor environmentally friendly behaviors. We sought to develop and test a tool to reliably capture data, increase environmental health knowledge, and engage youths as citizen scientists to examine and take action on their community's challenges. The Eyewitness Community Survey (ECS) was developed through several iterations of co-design.
View Article and Find Full Text PDFLimited health literacy and access to engaging, relevant, understandable health promotion and disease prevention materials are barriers to achieving and maintaining health. The We-Engage-4-Health program co-created the graphic-style story "Foamy Soap Fun" with community members to reinforce the importance of the primary preventive strategy-handwashing-in limiting spread of COVID-19. Pre/postsurveys were administered, and a modified focus group was conducted to learn community participants' preferences for reading stories (aloud together and/or silently to themselves), versus reading typical health promotion information sheets.
View Article and Find Full Text PDFWomens Health Issues
December 2022
Introduction: We analyzed the exclusion of pregnant and breastfeeding individuals and those capable of pregnancy in COVID-19 vaccine and clinical treatment trials.
Methods: Inclusion and exclusion criteria were extracted from all listed COVID-19 vaccine and treatment clinical trials from May 1, 2020, to October 31, 2020, using the U.S.
Acridinium 9-carboxylic acid derivatives have been extensively used as chemiluminescent labels in diagnostic assays. Triggering acridinium with basic hydrogen peroxide produces a highly strained dioxetanone intermediate, which converts into an acridone in an electronically excited state and emits light at 420-440 nm. Here, we introduce a novel acridinium-fluorescein construct emitting at 530 nm, in which fluorescein is covalently attached to the acridinium N-10 nitrogen via a propyl sulfonamide linker.
View Article and Find Full Text PDFMulticolor chemiluminescent acridinium derivatives were synthesized by attaching various common fluorophores to the N -acridinium position through a piperazine linker. Triggering of each acridinium derivative using alkaline hydrogen peroxide resulted in a chemiluminescence spectrum dominated by a strong emission (>95%) from the attached fluorophore. The highly quenched emission from the triggered acridinium, acting as a donor, points to a highly efficient intramolecular energy transfer in acridinium-based chemiluminophore-fluorophore tandems.
View Article and Find Full Text PDFObjective: This study evaluated whether providing the Fruits and Vegetables (F/V) required by the Healthy Hunger-Free Kids Act (HHFKA) increased phytochemical/antioxidant content of school lunches. Additionally, the ability of adolescents to apply their nutritional knowledge following participation in a nutrition-focused science-based curriculum was assessed.
Methods: Changes in antioxidant/phytochemical content from F/V offered in school lunch menus were analyzed Pre-and Post-HHFKA.
This article discusses the behavioral genetic (BG) approach to parenting. Parenting is considered a phenotype that can be influenced by nature and nurture. Genetic contributions to parenting are conceptualized as evidence of genotype-environment correlation (rGE).
View Article and Find Full Text PDFBackground: A new ARCHITECT® alpha fetoprotein (AFP) assay was developed to improve the linearity at the upper end of the calibration curve and to enhance other performance characteristics. In addition, this reformulation eliminated the possibility of falsely depressed samples at high AFP concentrations. The purpose of this study was to evaluate its analytical performance at multiple sites.
View Article and Find Full Text PDFCommunity Ment Health J
August 2009
The concept of recovery can be operationalized from either the point of view of the consumer, or from the perspective of the agency providing services. The Milestones of Recovery Scale (MORS) was created to capture aspects of recovery from the agency perspective. Evidence establishing the psychometric properties of the MORS was obtained in three efforts: Inter-rater reliability using staff at The Village, a multi-service organization serving the homeless mentally ill in Long Beach, California; inter-rater reliability was also obtained from Vinfen Corporation, a large provider of housing services to mentally ill persons in Boston, Massachusetts.
View Article and Find Full Text PDFDrug use is considered a main contributing factor to crime and violence. This research examined the evidence regarding the relationship between drug abuse and the occurrence of intimate partner violence. Current drug using men were assessed on aggression related personality variables, their drug use, and the occurrence of violence in their close relationships.
View Article and Find Full Text PDFDue to the pivotal roles that protein-protein interactions play in a plethora of biological processes, the design of therapeutic agents targeting these interactions has become an attractive and important area of research. The development of such agents is faced with a variety of challenges. Nevertheless, considerable progress has been made in the design of proteomimetics capable of disrupting protein-protein interactions.
View Article and Find Full Text PDFVirtual twins (VTs) are same-age unrelated siblings reared together from infancy who replicate twinship, but without the genetic relatedness. A 2005 report from the ongoing Fullerton Virtual Twin Study found an IQ intraclass correlation of .26 (p < .
View Article and Find Full Text PDFMany HIV prevention programs seek to reduce the risk of infection through increases in condom use. Condom use is often expressed as a proportion: the number of sexual contacts in which a condom is used divided by the total number of sexual contacts. The distribution of this proportion has several undesirable characteristics-the principal one is bimodality.
View Article and Find Full Text PDFThe incidence of interracial and interethnic dating and marriage in the United States has increased. This investigation examined dating and commitment choices as a function of ethnicity and sex among groups of Euro-American, Hispanic-American, Asian-American, and African-American college students. A convenience sample of college students comprising 329 heterosexual subjects (134 men, 195 women) was surveyed regarding their partner preferences for dating, visiting parents, marriage, and bearing children.
View Article and Find Full Text PDFThe neurohormonal theory of sexual orientation proposes that homosexual men and homosexual women are exposed prenatally to a hormonal environment that is similar to that of the other sex. Prenatal exposure to an opposite-sex hormonal environment may lead the nervous system to develop in a manner consistent with the opposite sex. If this cross-sex exposure occurs, one prediction would be that the cognitive ability profile of homosexual men would be similar to that of heterosexual women.
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